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BIS(4-HYDROXYCINNAMOYL)METHANE

BIS(4-HYDROXYCINNAMOYL)METHANE Structure
BIS(4-HYDROXYCINNAMOYL)METHANE
  • CAS No.33171-05-0
  • Chemical Name:BIS(4-HYDROXYCINNAMOYL)METHANE
  • CBNumber:CB9180475
  • Molecular Formula:C19H16O4
  • Formula Weight:308.33
  • MOL File:33171-05-0.mol
BIS(4-HYDROXYCINNAMOYL)METHANE Property
  • Melting point 221-223 ºC
  • Boiling point 551.3±45.0 °C(Predicted)
  • Density 1.285
  • storage temp. 2-8°C
  • solubility DMSO (Slightly), Methanol (Slightly, Heated)
  • pka 8.50±0.46(Predicted)
  • form solid
  • color Orange to Dark Orange
  • BRN 3149384
  • Stability Light Sensitive
  • LogP 3.155 (est)
  • FDA UNII 2EFO1BP34R
  • UNSPSC Code 85151701
  • NACRES NA.77
Safety
  • WGK Germany  :3
  • HS Code  :29145090
  • NFPA 704:
    0
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P305+P351+P338
BIS(4-HYDROXYCINNAMOYL)METHANE Price More Price(4)
  • Brand: Sigma-Aldrich(India)
  • Product number: B6938
  • Product name : Bisdemethoxycurcumin
  • Purity: ≥98% (HPLC), solid
  • Packaging: 5MG
  • Price: ₹12329.68
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: PHR3434
  • Product name : Bisdesmethoxycurcumin
  • Purity: certified reference material, pharmaceutical secondary standard
  • Packaging: 50MG
  • Price: ₹19863.88
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: B6938
  • Product name : Bisdemethoxycurcumin
  • Purity: ≥98% (HPLC), solid
  • Packaging: 25MG
  • Price: ₹48106.3
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 90594
  • Product name : Bisdemethoxycurcumin
  • Purity: analytical standard
  • Packaging: 10MG
  • Price: ₹22353.63
  • Updated: 2022/06/14
  • Buy: Buy

BIS(4-HYDROXYCINNAMOYL)METHANE Chemical Properties,Usage,Production

  • Uses Bisdemethoxycurcumin is one of the three major forms of curcuminoids found in the rhizomes of turmeric. Bisdemethoxycurcumin displays antioxidant, anti-inflammatory as well as chemotherapeutic activit y. Bisdemethoxycurcumin acts as an inhibitor of human pancreatic α-amylase, a target for type-2 diabetes .
  • Uses Bisdemethoxycurcumin has been used:
    • to test its inhibitory effect on cell cycle and mitochondrial function in gastric adenocarcinoma cells
    • to test it neuroprotective role against lead (Pb) induced toxicity in dopaminergic and noradrenergic systems of Meriones shawi
    • as a standard for calibration curve generation to quantify plasma curcuminoids using high-performance liquid chromatography-diode array detection (HPLC-DAD) and ultraviolet (UV)

  • Definition ChEBI: Bisdemethoxycurcumin is a beta-diketone that is methane in which two of the hydrogens are substituted by 4-hydroxycinnamoyl groups. It has a role as a metabolite and an EC 3.2.1.1 (alpha-amylase) inhibitor. It is a beta-diketone, a polyphenol, an enone and a diarylheptanoid. It is functionally related to a 4-coumaric acid.
  • General Description This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
  • Biochem/physiol Actions Bisdemethoxycurcumin (BDMC) is a derivative or curcumin, and represents one of the major active components of curcumin products isolated from Curcumae sp. BDMC shares similar anti-inflammatory properties with demethoxycurcumin. It inhibits LPS-induced nitric oxide (NO) production and expression of iNOS and COX2 in RAW264.7 cells by blocking NF-kB activation. BDMC also displays unique properties in that it enhances Abeta clearance by upregulating expression MGAT3 and TLR genes. BDMC potently inhibits AKR1B10.
BIS(4-HYDROXYCINNAMOYL)METHANE Preparation Products And Raw materials
Raw materials
Preparation Products
BIS(4-HYDROXYCINNAMOYL)METHANE Suppliers
Global(217)Suppliers
  • Supplier：
    BINBO BIOLOGICAL CO.,LTD
  • Tel： +8618629063126
  • Email：info@binbobiological.com
  • Country：China
  • ProdList：451
  • Advantage：58
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：sales@coreychem.com
  • Country：China
  • ProdList：29859
  • Advantage：58
  • Supplier：
    Alchem Pharmtech,Inc.
  • Tel：8485655694
  • Email：sales@alchempharmtech.com
  • Country：United States
  • ProdList：63687
  • Advantage：58
BIS(4-HYDROXYCINNAMOYL)METHANE Spectrum
33171-05-0, BIS(4-HYDROXYCINNAMOYL)METHANERelated Search:
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  • 34939-16-0
  • BISDEMETHOXYCURCUMIN,APOPTOTIC CURCUMINOID
  • 双去甲氧基姜黄素/HPLC
  • (1E,6E)-1,7-双(4-羟苯基)庚-1,6-二烯-3,5-二酮
  • 双去甲氧基姜黄素(姜黄素III/双脱氧基姜黄素)
  • 双去甲氧基姜黄素, 来源于姜
  • 双去甲氧基姜黄素标准品
  • 双去甲氧基姜黄素BISDEMETHOXYCURCUMIN
  • 化合物(1E,6E)-BIS(DEMETHOXY)CURCUMIN
  • 双去甲氧基姜黄素(双脱氧基姜黄素,姜黄素III)
  • 双-二甲氧基姜黄素
  • 双去甲氧基姜黄素
  • 二去甲氧基姜黄素
  • (1E,6E)-1,7-双(4-羟基苯基)-1,6-己二烯-3,5-二酮
  • 33171-05-0
  • (E,E)-Bisdemethoxycurcumin - Bio-X ?
  • Bisdemethoxycurcumin, Apoptotic curcuminoid
  • Bisdemethoxycurcumin/1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)-
  • (E,E)-Curcumin III,Bisdemethoxycurcumin,inhibit,(E,E)-Didemethoxycurcumin,Inhibitor,Apoptosis,Autophagy,(E,E)-Bisdemethoxycurcumin
  • (1E,6E)-Bis(demethoxy)curcumin
  • BISDEMETHOXY CURCUMIN
  • Misdemeanour
  • BIS(4-HYDROXYCINNAMOYL)METHANE USP/EP/BP
  • 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)-
  • Bisdemethoxycurcumin(b)
  • Bisdemethoxycurcumin(BDMC)
  • Bisdemethoxycurcumin, 98%, from Zingiber officinale Rosc.
  • Deleted CAS No: 22608-12-4, 85801-92-9, 91884-88-7, 104024-29-5
  • Bis(p-hydroxycinnamoyl)methane
  • 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (E,E)-
  • Didemethoxycurcumin
  • BIS(4-HYDROXYCINNAMOYL)METHANE
  • BIS-DESMETHOXYCURCUMIN
  • DEMETHOXYCURCUMIN, BIS-
  • CURCUMIN 3
  • (E,E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
  • (E,E)-BisdeMethoxycurcuMin

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