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CAPTOPRIL DISULFIDE

CAPTOPRIL DISULFIDE Structure
CAPTOPRIL DISULFIDE
  • CAS No.64806-05-9
  • Chemical Name:CAPTOPRIL DISULFIDE
  • CBNumber:CB9129834
  • Molecular Formula:C18H28N2O6S2
  • Formula Weight:432.55
  • MOL File:64806-05-9.mol
CAPTOPRIL DISULFIDE Property
  • Melting point 224-226°C
  • Boiling point 714.8±60.0 °C(Predicted)
  • Density 1.383±0.06 g/cm3(Predicted)
  • storage temp. -20°C Freezer
  • solubility DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly, Sonicated)
  • form Solid
  • pka 3.29±0.20(Predicted)
  • color White to Off-White
  • FDA UNII Y21D2C2453
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
  • WGK Germany  :3
  • HS Code  :2933999552
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

CAPTOPRIL DISULFIDE Chemical Properties,Usage,Production

  • Description Captopril disulfide is a metabolite and symmetrical disulfide form of the angiotensin converting enzyme (ACE) inhibitor captopril . Captopril disulfide is the main degradation product of captopril and is formed by oxidation. It is a potential impurity in commercial preparations of captopril. Captopril disulfide inhibits angiotensin I-induced increases in mean arterial pressure in anesthetized dogs (ID50 = 0.231 mg/kg, i.v.).
  • Chemical Properties White Solid
  • Uses Captopril Disulfide (Captopril EP Impurity A) is a metabolite of Captopril. A new antihypertensive agent.
  • Definition ChEBI: An organic disulfide in which the disulfide bond links two units of captopril. It is a secondary metabolite of captopril.
CAPTOPRIL DISULFIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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CAPTOPRIL DISULFIDE Spectrum
64806-05-9, CAPTOPRIL DISULFIDERelated Search:
  • Pharmaceuticals
  • Metabolites & Impurities
  • Intermediates & Fine Chemicals
  • 杂质对照品
  • 245-卡托普利
  • 抑制剂
  • 对照品-杂质对照品
  • 标准品
  • 中药对照品
  • 43255
  • C18H28N2O6S2
  • 64806-05-09
  • 化合物 CAPTOPRIL DISULFIDE
  • (2S,2'S)-1,1'-((2S,2'S)-3,3'-二硫烷二基双(2-甲基丙酰基))双(吡咯烷-2-羧酸)
  • 卡托普利杂质Ⅰ(卡托普利二硫化物)(2S,2'S)-1,1'_-[二硫烷二基双[(2S)-2-甲基-1-氧代丙 烷-3,1-二基]-双[吡咯烷-2-羧酸
  • SQ14,551|||SQ 14,551|||SQ-14,551
  • 卡托普利杂质1(卡托普利EP杂质A)
  • 卡托普利杂质Ⅰ
  • 卡托普利杂质01
  • 卡托普利12
  • 卡托普利二硫化物 USP标准品
  • 卡托普利杂质A(EP) 标准品
  • CAPTOPRIL EP杂质 A
  • 卡托普利杂质A(EP)
  • 卡托普利二硫醚
  • 卡托普利杂质Ⅰ(卡托普利二硫化物)(2S,2'S)-1,1'_-[二硫烷二基双[(2S)-2-甲基-1-氧代丙 烷-3,1-二基]-双[吡咯烷-2-羧酸]]
  • 卡托普利杂质Ⅰ（卡托普利二硫化物）（2S，2'S）-1，1'_-[二硫烷二基双[（2S）-2-甲基-1-氧代丙 烷-3，1-二基]-双[吡咯烷-2-羧酸]]
  • 卡托普利杂质A
  • 卡托普利EP杂质A
  • 卡托普利二硫化物
  • 64806-05-9
  • 1,1'-[Disulfanediylbis-[(2S)-2-methyl-1-oxopropane-3,1-diyl]]-bis[(2S)-pyrrolidine-2-carboxylic] Aci
  • 1,1′-[disulfanediylbis[(2S)-2-methyl-1-oxopropane-3,1- diyl]]bis[(2S)-pyrrolidine-2-carboxylic] acid
  • (2S,2'S)-1,1'-((2S,2'S)-3,3'-disulfanediylbis(2-methylpropanoyl))bis(pyrrolidine-2-carboxylic acid)
  • L-Proline, 1,1'-[dithiobis[(2S)-2-methyl-1-oxo-3,1-propanediyl]]bis-
  • 1,1'-[Disulfanediylbis-[(2S)-2-meth
  • Captopril-Disuphide
  • Captopril Impurity 1(Captopril EP Impurity A)
  • (2S,2'S)-1,1'-[Disulphanediylbis[(2S)-2-methyl-1-oxopropane-3,1-diyl]-bis[pyrrolidine-2-carboxylic] acid
  • Imp. A (EP):1,1'-[Disulfanediylbis-[(2S)-2-methyl-1-oxopropane-3,1-diyl]]-bis[(2S)-pyrrolidine-2-carboxylic] Acid(Captopril Disulfide)
  • Captopril ImpurityⅠ:Captopril Disulfide{ 1,1'-[Dithiobis[(2S)-2-methyl-1-oxo-3,1-propanediyl]]bis-L-proline CAPTOPRDS}
  • Captopril Disulfide (1091221)
  • Captopril ImpurityⅠ:Captopril Disulfide{ 1,1’-[Dithiobis[(2S)-2-methyl-1-oxo-3,1-propanediyl]]bis-L-proline CAPTOPRDS}
  • Captopril EP Impurity A (Captopril disulphide)
  • Captopril EP Impurity A-d6
  • CaptoprilDisuphide(CaptoprilImpurityI)
  • Captopril EP IMpurity A
  • Captopril IMp. A (BP)
  • Captopril Disulde (100 mg)
  • Captopril Disulfide (100 mg)
  • 1,1'-[Dithiobis[(S)-2-methyl-1-oxo-3,1-propanediyl]]bis-L-proline
  • (1,1-[Dithiobis[(2S)-2-methyl-1-oxo-3,1-propanediyl]]bis-L-proline CAPTOPRDS
  • SQ 14551
  • CAPTOPRDS
  • 1,1'-[Dithiobis[(2S)-2-methyl-1-oxo-3,1-propanediyl]]bis-L-proline
  • CAPTOPRIL DISULPHIDE BP(CRM STANDARD)
  • CAPTOPRIL DISULPHIDE BP STANDARD(CRM STANDARD)
  • Captopril Impurity J

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