ChemicalBook > CAS DataBase List > 4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)-
4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)-
4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)-
- CAS No.2169-44-0
- Chemical Name:4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)-
- CBNumber:CB91243115
- Molecular Formula:C20H23NO4
- Formula Weight:341.4
- MOL File:2169-44-0.mol
4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)- Property
- Melting point 102.5°C
- Boiling point 477.03°C (rough estimate)
- Density 1.2064 (rough estimate)
- refractive index 1.5614 (estimate)
- solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form Powder
- FDA UNII 11558LRZ50
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H320
- Precautionary statements P264-P337+P313-P305+P351+P338
4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)- Chemical Properties,Usage,Production
-
Description
This alkaloid, identified as the N-methyl derivative of laurotetanine (q. v.), has
been isolated from Escholtzia californica Cham., Phylica fengerialla and P.
rogersii Pillans. The base is known in two modifications; as an amorphous
powder and a colourless crystals from MeOH containing 0.5 mole of solvent,
identical with rogersine (q.v.). The alkaloid has [α]D + 1110 (c 0.86, MeOH) and
the ultraviolet spectrum in EtOH has absorption maxima at 219, 282 and
304 rn[J.; while that in alkaline solution (0.05 N/NaOH) has absorption maxima
at 223 and 329 mil.
The alkaloid yields a crystalline hydriodide, m.p. 245°C; the methiodide, m.p. 199-2000 C and the Q-ethyl (-)-tartrate, m.p. 206-7°C (dec.) giving a methiodide, m.p. 213° C. - Uses Lauroscholtzine (N-Methyllaurotetanine), a natural alkaloid, is a 5-HT1A receptor agonist[1].
- target 5-HT Receptor | Antifection
-
References
Arndt, Baarschers., J. Chern. Soc., 2244 (1964)
Manske, Shin., Can. J. Chern., 43,2180 (1965)
Baarschers, Arndt., Tetrahedron, 21,2155 (1965)
Pachler, Arndt, Baarschers., ibid, 21,2159 (1965)
4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)- Preparation Products And Raw materials
Raw materials
Preparation Products
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2169-44-0, 4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)-Related Search:
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- 4H-Dibenzo[de,g]quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6aS)-
- (6aS)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-9-ol
- NSC 247564
- NSC 247506
- Boldine 2-methyl ether
- Rogersine
- Methyllaurotetanine
- Lauroscholtzine
- (6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-9-ol
- (+)-N-Methyllaurotetamine
- (+)-6-Methyl-1,2,10-trimethoxy-5,6,6aα,7-tetrahydro-4H-dibenzo[de,g]quinoline-9-ol
- 4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)-