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1-Hydroxybenzotriazole hydrate

1-Hydroxybenzotriazole hydrate Structure
1-Hydroxybenzotriazole hydrate
  • CAS No.123333-53-9
  • Chemical Name:1-Hydroxybenzotriazole hydrate
  • CBNumber:CB8775919
  • Molecular Formula:C6H7N3O2
  • Formula Weight:153.14
  • MOL File:123333-53-9.mol
1-Hydroxybenzotriazole hydrate Property
  • Melting point 155-158 °C(lit.)
  • Boiling point 248.8°C (rough estimate)
  • Density 1.065 g/cm
  • refractive index 1.6910 (estimate)
  • storage temp. Keep in dark place,Inert atmosphere,Room temperature
  • solubility DMF: 100 mg/mL, clear
  • form Solid
  • color White to Off-White
  • Water Solubility slightly soluble
  • BRN 4515
  • Stability Hygroscopic
  • CAS DataBase Reference 123333-53-9(CAS DataBase Reference)
  • FDA UNII S72K7GY45F
  • UNSPSC Code 12352000
  • NACRES NA.22
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H207-H319-H412
  • Precautionary statements P210-P212-P230-P233-P280-P370+P380+P375-P501
1-Hydroxybenzotriazole hydrate Price More Price(19)
  • Brand: Sigma-Aldrich(India)
  • Product number: 711489
  • Product name : 1-Hydroxybenzotriazole hydrate
  • Purity: wetted with not less than 20 wt. % water, 97%
  • Packaging: 50G
  • Price: ₹9352.8
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 711489
  • Product name : 1-Hydroxybenzotriazole hydrate
  • Purity: wetted with not less than 20 wt. % water, 97%
  • Packaging: 250G
  • Price: ₹21801.55
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 54802
  • Product name : 1-Hydroxybenzotriazole hydrate
  • Purity: ≥97.0% (T)
  • Packaging: 10G
  • Price: ₹2771.2
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 54802
  • Product name : 1-Hydroxybenzotriazole hydrate
  • Purity: ≥97.0% (T)
  • Packaging: 10G
  • Price: ₹2771.2
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 157260
  • Product name : 1-Hydroxybenzotriazole hydrate
  • Purity: wetted with not less than 14 wt. % water, 98%
  • Packaging: 25G
  • Price: ₹3074.3
  • Updated: 2022/06/14
  • Buy: Buy

1-Hydroxybenzotriazole hydrate Chemical Properties,Usage,Production

  • Chemical Properties White to off-white powder
  • Uses 1-Hydroxybenzotriazole hydrate can be used as a condensation reagent to prepare:
    • Poly-γ-glutamic acid methyl ester from a dimer of γ-glutamic acid.
    • Oxadiazoles via cyclo condensation of amidoximes with trifluoroacetic anhydride or benzoic acid derivatives.

  • Uses A common additive for peptide coupling.
  • Uses additive for oligonucleotide couplings and in racemization-free peptide couplings
  • General Description 1-Hydroxybenzotriazole is a coupling reagent used to synthesize amides by the condensation reaction between the activated ester/acid and the amino group of protected amino acids. It is also used as a racemization suppressor during peptide synthesis.
  • reaction suitability reaction type: Addition Reactions
  • Toxics Screening Level The ITSL 1-Hydroxy benzotriazole has been changed from 0.04 μg/m3 to 0.1 μg/m3 based on an annual averaging time.
1-Hydroxybenzotriazole hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
1-Hydroxybenzotriazole hydrate Suppliers
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1-Hydroxybenzotriazole hydrate Spectrum
123333-53-9, 1-Hydroxybenzotriazole hydrateRelated Search:
  • 123333-53-9
  • FINE Chemical & INTERMEDIATES
  • Heterocycles
  • Nucleotides
  • Bases & Related Reagents
  • Peptide
  • Heterocyclic Compounds
  • 中医中间体
  • 杂质对照品
  • 生化试剂
  • 其它原料及中间体
  • 多肽缩合剂
  • 原料药
  • 化学试剂
  • 通用生化试剂-氨基酸
  • 化工中间体
  • 生化试剂-氨基酸类
  • 化学试剂
  • 肽键缩合剂
  • 杂环化合物
  • 多肽耦合
  • 氨基酸
  • 中间体
  • 缩合试剂
  • 化学生物学
  • 苯并杂环
  • 医药原料
  • 氨基酸类
  • Synthetic Reagents
  • Coupling
  • Active Esters/Additives
  • C6H5N3OxxH2O
  • C6H5N3OxH2O
  • C6H5N3OH2O
  • 1-羟基苯并三唑一水物(HOBT.H2O)
  • HOBT.H2O(1-羟基-苯骈三唑一水)
  • 1-羟基苯并三氮唑X水合物
  • 1-羟基苯并三氮唑一水物/1-羟基苯并三唑一水物
  • 1-羟基苯并三氮唑一水物/对羟基苯三唑一水/1-羟基苯骈三氮唑一水/1-羟基苯并三唑一水/HOBT
  • 1-羟基苯并三唑一水物(HOBT.H20)
  • 1-羟基苯并三唑一水物 1-HYDROXYBENZOTRIAZOLE HYDRATE
  • 1-羟基苯骈三唑一水合物
  • 对羟基苯三唑一水
  • 1-羟基苯骈三氮唑一水
  • 1-羟氰基苯并三唑
  • 1-羟基苯并三唑水合物, 98%+
  • 1-羟基苯并三氮唑一水合物
  • 1-羟基苯并三唑一水物 100G
  • 1-羟基苯并三氮唑一水物/对羟基苯三唑一水/1-羟基苯骈三氮唑一水/1-羟基苯并三唑一水
  • 1-羟基苯骈三氮唑一水物
  • 1-羟基苯并三唑水合物
  • 1-羟基苯并噻唑(停产061218)
  • 1-羟基苯并三唑一水物
  • 1-羟基苯并三唑一水
  • 1-羟基苯并三唑合水合物
  • HOBT.H2O, 1-羟基苯并三唑一水物
  • 123333-53-9
  • 1-Hydroxybenzotriazole hydrate wetted (>20 wt % water)

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