Chemical Properties
White powder
Uses
DL-2-Aminopimelic Acid is a weak agonist of glutamate receptors and also reduces the sensitivity of leech glutamate receptors to glutamate[1].
Definition
ChEBI: 2-aminopimelic acid is an amino dicarboxylic acid that is heptanedioic acid in which a hydrogen at position 2 is replaced by an amino group. It is a component of the cell wall peptidoglycan of bacteria. It has a role as a bacterial metabolite. It is an amino dicarboxylic acid and a non-proteinogenic alpha-amino acid.
References
[1] V A James, et al. Structure-activity studies on an excitatory receptor for glutamate on leech Retzius neurons. Br J Pharmacol. 1980 Apr;68(4):711-7. DOI:
10.1111/j.1476-5381.1980.tb10864.x
