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S-(4-NITROBENZYL)-6-THIOINOSINE

S-(4-NITROBENZYL)-6-THIOINOSINE Structure
S-(4-NITROBENZYL)-6-THIOINOSINE
  • CAS No.38048-32-7
  • Chemical Name:S-(4-NITROBENZYL)-6-THIOINOSINE
  • CBNumber:CB8713230
  • Molecular Formula:C17H17N5O6S
  • Formula Weight:419.41
  • MOL File:38048-32-7.mol
S-(4-NITROBENZYL)-6-THIOINOSINE Property
  • Melting point 187-190 °C(lit.)
  • Boiling point 770.2±70.0 °C(Predicted)
  • Density 1.3904 (rough estimate)
  • refractive index 1.6460 (estimate)
  • storage temp. 2-8°C
  • solubility 0.1 M HCl: slightly soluble
  • form solid
  • pka 13.08±0.70(Predicted)
  • color white
  • CAS DataBase Reference 38048-32-7(CAS DataBase Reference)
  • FDA UNII GV1L2DZM2Z
  • UNSPSC Code 12352202
  • NACRES NA.77
Safety
  • Safety Statements  :24/25
  • WGK Germany  :3
  • RTECS  :UO9025000
  • HS Code  :29349990
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
S-(4-NITROBENZYL)-6-THIOINOSINE Price More Price(3)
  • Brand: Sigma-Aldrich(India)
  • Product number: N2255
  • Product name : S-(4-Nitrobenzyl)-6-thioinosine
  • Purity: ≥98%, solid
  • Packaging: 25MG
  • Price: ₹7231.1
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: N2255
  • Product name : S-(4-Nitrobenzyl)-6-thioinosine
  • Purity: ≥98%, solid
  • Packaging: 100MG
  • Price: ₹19874.7
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: N2255
  • Product name : S-(4-Nitrobenzyl)-6-thioinosine
  • Purity: ≥98%, solid
  • Packaging: 250MG
  • Price: ₹43754.65
  • Updated: 2022/06/14
  • Buy: Buy

S-(4-NITROBENZYL)-6-THIOINOSINE Chemical Properties,Usage,Production

  • Chemical Properties Off-White Solid
  • Uses It is a prototype inhibitor of the human equilibrative nucleoside transporter (hENT1), and is a high affinity ligand with a Kd of 0.1-1.0 nM. Nucleoside transporter inhibitors have potential therapeutic applications as anticancer, antiviral, cardio
  • Uses S-(4-Nitrobenzyl)-6-thioinosine is a nucleoside analog and an inhibitor of the human equilibrative nucleoside transporter (hENT1) (1,2,3). Nucleoside transporter inhibitors are useful compounds to investigate anticancer, antiviral, cardioprotective, and neuroprotective agents.
  • Definition ChEBI: NBMPR is a purine nucleoside.
  • General Description S-(4-Nitrobenzyl)-6-thioinosine (NBTI) belongs to the family of S6-substituted 6-thiopurine nucleosides, which regulate nucleoside transport mechanisms in animals. It acts as a ligand of adenosine transporter. Binding sites for NBTI is located on brain capillaries. It functions as a covalent photoaffinity probe for nucleoside transport.
  • Biological Activity Equilibrative nucleoside transporter 1 (ENT1) inhibitor (K i values are 0.4 and 2800 nM for hENT1 and hENT2 respectively).
  • Biochem/physiol Actions Inhibitor of equilibrative nucleoside transporters (ENTs), particularly adenosine transporters, in central nervous system and vascular smooth muscle.
  • storage Store at +4°C
S-(4-NITROBENZYL)-6-THIOINOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
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S-(4-NITROBENZYL)-6-THIOINOSINE Spectrum
38048-32-7, S-(4-NITROBENZYL)-6-THIOINOSINERelated Search:
  • Sulfur & Selenium Compounds
  • Nucleotides
  • Inhibitors
  • Heterocycles
  • Bases & Related Reagents
  • 抑制剂
  • 药靶配体
  • 合成
  • C17H17N5O6S
  • S-(4-硝基苄基)-6-硫代肌苷,10 MM DMSO 溶液
  • S-(4-硝基芐基)-6-硫代肌苷
  • (S)-(4-硝基苯甲基)-6-硫肌苷
  • S-(4-硝基苄基)-6-硫肌苷
  • 6-[(4-硝基苄基)硫代]-9-Β-D-呋喃核糖基嘌呤
  • S-(4-硝基苄基)-6-硫代肌苷
  • 38048-32-7
  • 6-((4-nitrobenzyl)thio)-9-β-D-ribofuranosylpurine
  • NBMPR (Nitrobenzylthioinosine)
  • <i>S</i>-(4-Nitrobenzyl)-6-thioinosine
  • Nitrobenzylthioinosine, 10 mM in DMSO
  • S6-(4-nitrylbenzyl)thioinosine
  • NBMPR
  • Inosine, 6-S-[(4-nitrophenyl)methyl]-6-thio-
  • (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((4-nitrobenzyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
  • S-(4-Nitrobenzyl)-6-thioinosine,99%
  • 6-[[(4-Nitrophenyl)methyl]thio]-9-(β-D-ribofuranosyl)-9H-purine
  • 6-[(4-Nitrobenzyl)thio]-9-β-D-ribofuranosyl-9H-purine
  • 4-Nitrobenzyl-6-mercaptoinosine
  • NBMPR, NBTI, 6-[(4-Nitrobenzyl)thio]-9-β-D-ribofuranosylpurine
  • S-(p-Nitrobenzyl)-6-mercapto-9--D-ribofuranosylpurine
  • NSC 296962
  • 6-S-[(4-Nitrophenyl)methyl]-6-thioinosine
  • 6-[(4-Nitrobenzyl)-mercapto]-inosine
  • 6-[(4-nitrobenzyl)thio]-9-β-d-ribofuranosylpurine
  • S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR)
  • S-(P-NITROBENZYL)-6-THIOINOSINE 98+%
  • S-(4-NITROBENZYL)-6-THIOINOSINE (NBTI) P OTENT ADENOSINE UPTA
  • nitrobenzylthioinosine
  • 6-[(4-NITROBENZYL)THIO]-9-BETA-D-RIBOFURANOSYLPURINE
  • 6-(p-nitrobenzylthio)inosine
  • 6-(((4-nitrophenyl)methyl)thio)-9-beta-d-ribofuranosyl-9h-purine
  • 6-(((4-nitrophenyl)methyl)thio)-9-beta-d-ribofuranosyl-9h-purin
  • 4-nitrobenzylthioinosine
  • NBTI
  • S-(4-NITROBENZYL)-6-THIOINOSINE
  • S-(P-NITROBENZYL)-6-THIOINOSINE

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