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N,N-Dimethyltryptamine

N,N-Dimethyltryptamine Structure
N,N-Dimethyltryptamine
  • CAS No.61-50-7
  • Chemical Name:N,N-Dimethyltryptamine
  • CBNumber:CB8498045
  • Molecular Formula:C12H16N2
  • Formula Weight:188.27
  • MOL File:61-50-7.mol
N,N-Dimethyltryptamine Property
  • Melting point 42-44°C
  • Boiling point bp 60-80°
  • Density 1.0580 (rough estimate)
  • refractive index 1.5430 (estimate)
  • Flash point 9℃
  • storage temp. Store at -20°C
  • solubility DMSO: soluble15mg/mL, clear
  • form powder
  • pka 8.68 (ethanol-water)
  • color white to beige
  • FDA UNII WUB601BHAA
  • NIST Chemistry Reference N,N-Dimethyltryptamine(61-50-7)
Safety
  • RIDADR  :1544
  • WGK Germany  :3
  • HazardClass  :6.1(b)
  • PackingGroup  :III
  • Hazardous Substances Data :61-50-7(Hazardous Substances Data)
  • DEA Controlled Substances :CSCN: 7435
    CAS SCH: I
    NARC: N
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H336
  • Precautionary statements P261-P271-P304+P340+P312-P403+P233-P405-P501

N,N-Dimethyltryptamine Chemical Properties,Usage,Production

  • Chemical Properties Tan Solid
  • Uses A labelled endogenous Sigma-1 receptor regulator.
  • Uses It is an endogenous Sigma-1 receptor regulator.
  • Definition ChEBI: A tryptamine derivative having two N-methyl substituents on the side-chain.
  • Synthesis Reference(s) The Journal of Organic Chemistry, 59, p. 3738, 1994 DOI: 10.1021/jo00092a046
  • General Description Dimethyltryptamine is a very weak hallucinogen, activeonly by inhalation or injection, with a short duration of action.It possesses pronounced sympathomimetic (NE) sideeffects.
  • Biological Activity Endogenous σ 1 receptor ligand and psychoactive plant compound (K i = 14.8 μ M). Binding to σ 1 inhibits voltage-gated Na + channels and is responsible for the behavioral effects of DMT. Also a 5-HT 2A receptor agonist and inhibitor of 5-HT uptake at plasma membrane serotonin transporters (SERT) (K i = 4.0 μ M).
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N,N-Dimethyltryptamine Spectrum
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  • N,N-DIMETHYLTRYPTAMINE METHANOL*SOLUTION

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