ChemicalBook > CAS DataBase List > Chorionic Gonadotropin
Chorionic Gonadotropin
Chorionic Gonadotropin
- CAS No.9002-61-3
- Chemical Name:Chorionic Gonadotropin
- CBNumber:CB8353322
- Molecular Formula:C17H28
- Formula Weight:232.40422
- MOL File:9002-61-3.mol
Chorionic Gonadotropin Property
- storage temp. 2-8°C
- solubility H2O: soluble1ML/vial
- form lyophilized powder
- color White to off-white
- biological source human urine
- Water Solubility water: soluble
- NCI Dictionary of Cancer Terms APL
- FDA UNII 20ED16GHEB
- NCI Drug Dictionary Follutein
- ATC code G03GA01,G03GA08
- UNSPSC Code 12352209
- NACRES NA.77
Safety
- Hazard Codes :B,Xn
- Risk Statements :63-62
- Safety Statements :22-36-36/37
- WGK Germany :3
- RTECS :MD6953000
- HS Code :2937190000
- Hazardous Substances Data :9002-61-3(Hazardous Substances Data)
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H361
- Precautionary statements P281
Chorionic Gonadotropin Price
More Price(15)
- Brand: Sigma-Aldrich(India)
- Product number: CG5
- Product name : Chorionic gonadotropin human
- Purity: lyophilized powder, vial of ~5,000?IU
- Packaging: 1VIAL
- Price: ₹15685.43
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: CG5
- Product name : Chorionic gonadotropin human
- Purity: lyophilized powder, vial of ~5,000?IU
- Packaging: 10VIALS
- Price: ₹94610.5
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: CG10
- Product name : Chorionic gonadotropin human
- Purity: lyophilized powder, vial of ~10,000?IU
- Packaging: 1VIAL
- Price: ₹20708.23
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: CG10
- Product name : Chorionic gonadotropin human
- Purity: lyophilized powder, vial of ~10,000?IU
- Packaging: 10VIALS
- Price: ₹130116.5
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: C8554
- Product name : Chorionic gonadotropin human
- Purity: lyophilized powder, suitable for mouse embryo cell culture
- Packaging: 50IU
- Price: ₹7848.13
- Updated: 2022/06/14
- Buy: Buy
Chorionic Gonadotropin Chemical Properties,Usage,Production
- Chemical Properties White or yellowish-white, amorphous powder.
-
Uses
Chorionic gonadotropin human has been used:
- to induce oocyte maturation in cultured follicles
- along with pregnant mare serum gonadotropin (PMSG) to induce superovulation in mice
- as medium component for fetal testes culture to aid steroidogenic responsiveness
- Uses Gonad-stimulating principle.
- Production Methods CG is produced in the chorion.
- Application Human chorionic gonadotropin (hCG) is a chemical produced by the trophoblast tissue, which is usually present in the early embryo and will eventually become part of the placenta. Measuring hCG levels helps to identify normal, pathological and miscarried pregnancies. Measuring hCG is also beneficial for many cancers including choriocarcinoma and extrauterine malignancies.
- brand name A.P.L. (Ferring Pharmaceuticals); Follutein (Bristol-Myers Squibb); Pregnyl (Organon).
- General Description Glycoprotein hormone consisting of a 92-amino acid α-chain which is identical to that of LH, FSH, and TSH; and a distinct 149-amino acid β-chain. Produced by chorionic tissue and responsible for maintaining the corpus luteum during early pregnancy. Also produced by trophoblast cell neoplasms, which are marked by elevated free hCG β-chains and hyperglycosylated hCG.
- Biochem/physiol Actions Elevated levels of hCG is observed in trophoblastic cancer. hCG levels are indicators of pregnancy and β subunit is majorly present in urine samples. hCG isoform detection is useful in the diagnosis and management of trophoblastic related diseases including carcinomas.
- Clinical Use Choriogonadotropin alfa is obtained by rDNA technology and is biologically and chemically identical to hCG of natural origin. It is used, like hCG of natural origin, for inducing ovulation in women with anovulatory infertility. Following proper pretreatment with a GnRH antagonist or superagonist to desensitize the pituitary, women participating in ART are treated with a folliclestimulating agent (e.g., menotropins) to effect the final maturation of the follicles within the ovaries. Ultrasonograms are used to determine proper follicle maturation before the administration of choriogonadotropin alfa to induce ovulation. A distinct advantage of this product is that it can be self-administered by the patient via SC injection.
- Veterinary Drugs and Treatments The veterinary product’s labeled indication is for “parenteral use in cows for the treatment of nymphomania (frequent or constant heat) due to cystic ovaries.” It has been used for other purposes in several species; refer to the Dosage section for more information.
Chorionic Gonadotropin Preparation Products And Raw materials
Raw materials
Preparation Products
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9002-61-3, Chorionic GonadotropinRelated Search:
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- Non-human chorionic gonadotrophin
- HCG Human chorionic gonadotropin 5000IU/10000IU
- Human Chorionic Gonadotropin (1 vial, 530 USP Units per package) (COLD SHIPMENT REQUIRED)
- Human Chorionic Gonadotrophin(Sources: Urine from pregnant woman)
- Chorionic Gonadotrophin (CG) and Luteinizing Hormone (LH)
- Gonadotropin, chorionisch
- HCG 5000IU