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Mal-PEG1-t-butyl ester

Mal-PEG1-t-butyl ester Structure
Mal-PEG1-t-butyl ester
  • CAS No.810677-16-8
  • Chemical Name:Mal-PEG1-t-butyl ester
  • CBNumber:CB83062528
  • Molecular Formula:C13H19NO5
  • Formula Weight:269.29
  • MOL File:810677-16-8.mol
Mal-PEG1-t-butyl ester Property
  • solubility Soluble in DMSO, DCM, DMF
  • form Solid
  • color White to off-white
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Mal-PEG1-t-butyl ester Chemical Properties,Usage,Production

  • Description Mal-PEG1-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
  • Uses Mal-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • IC 50 Alkyl/ether
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Mal-PEG1-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Mal-PEG1-t-butyl ester Suppliers
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  • Supplier：
    TargetMol Chemicals Inc.
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  • Supplier：
    Aladdin Scientific
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  • Email：tp@aladdinsci.com
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Mal-PEG1-t-butyl ester Spectrum
810677-16-8, Mal-PEG1-t-butyl esterRelated Search:
  • 抑制剂
  • 化合物 MAL-PEG1-BOC
  • 马来酰亚胺-聚乙二醇-叔丁酯
  • 810677-16-8
  • tert-butyl 3-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]propanoate
  • Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-, 1,1-dimethylethyl ester
  • Mal-PEG1-Boc
  • Mal-PEG1-t-butyl ester

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