ChemicalBook > CAS DataBase List > Mal-PEG4-amine TFA salt
Mal-PEG4-amine TFA salt
Mal-PEG4-amine TFA salt
- CAS No.2512227-13-1
- Chemical Name:Mal-PEG4-amine TFA salt
- CBNumber:CB78286548
- Molecular Formula:C16H25F3N2O8
- Formula Weight:430.38
- MOL File:2512227-13-1.mol
Mal-PEG4-amine TFA salt Property
- form Liquid
- color Colorless to light yellow
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Mal-PEG4-amine TFA salt Chemical Properties,Usage,Production
- Uses Mal-PEG4-C2-NH2 TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
- Biological Activity Mal-PEG4-C2-NH2 TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
- IC 50 PEGs
- References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Mal-PEG4-amine TFA salt Preparation Products And Raw materials
Raw materials
Preparation Products
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2512227-13-1, Mal-PEG4-amine TFA saltRelated Search:
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