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DifluoroiodoMethyl phenyl sulfone

DifluoroiodoMethyl phenyl sulfone Structure
DifluoroiodoMethyl phenyl sulfone
  • CAS No.802919-90-0
  • Chemical Name:DifluoroiodoMethyl phenyl sulfone
  • CBNumber:CB82709840
  • Molecular Formula:C7H5F2IO2S
  • Formula Weight:318.08
  • MOL File:802919-90-0.mol
DifluoroiodoMethyl phenyl sulfone Property
  • Boiling point 312.4±42.0 °C(Predicted)
  • Density 1.975±0.06 g/cm3(Predicted)
  • storage temp. 2-8°C(protect from light)
Safety
  • Safety Statements  :24/25
  • HS Code  :29309090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P305+P351+P338

DifluoroiodoMethyl phenyl sulfone Chemical Properties,Usage,Production

  • Description A visible light-catalysed direct and regioselective (phenylsulfonyl) difluoromethylation of imidazo[1,2-A]pyridines and benzo[d]-imidazo[2,1-b]thiazoles was carried out by DifluoroiodoMethyl phenyl sulfone under mild conditions. This synthetic methodology enables the introduction of a CF2SO2Ph group in an efficient and regioselective reaction through C-H bond functionalization with a broad substrate scope in good to excellent yields.
  • Uses Iododifluoromethyl phenyl sulfone can be used for the difluoromethylation of alkenes and alkynes initiated by triethylborane/air or arenediazonium salt/titanium chloride in moderate to good yields.
  • Reactions (1) Difluoromethylation of terminal alkenes and alkynes.
    DifluoroiodoMethyl phenyl sulfone
  • References [1] GUO-JIE YIN; W. F; Mei Zhu. Visible-light mediated regioselective (phenylsulfonyl)difluoromethylation of fused imidazoles with iododifluoromethyl phenyl sulfone[J]. Heterocyclic Communications, 2017. DOI:10.1515/hc-2017-0101.
    [2] YA LI. Radical (Phenylsulfonyl)difluoromethylation with Iododifluoromethyl Phenyl Sulfone[J]. The Journal of Organic Chemistry, 2007. DOI:10.1021/jo070618s.
DifluoroiodoMethyl phenyl sulfone Preparation Products And Raw materials
Raw materials
Preparation Products
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DifluoroiodoMethyl phenyl sulfone Spectrum
  • 苯类
  • C7H5F2IO2S
  • (二氟碘甲基)磺酰]苯
  • 二氟碘甲基苯基砜
  • 802919-90-0
  • Benzene, [(difluoroiodomethyl)sulfonyl]-
  • (difluoroiodomethylsulfonyl)benzene
  • DifluoroiodoMethyl phenyl sulfone