ChemicalBook > CAS DataBase List > DifluoroiodoMethyl phenyl sulfone
DifluoroiodoMethyl phenyl sulfone
DifluoroiodoMethyl phenyl sulfone
- CAS No.802919-90-0
- Chemical Name:DifluoroiodoMethyl phenyl sulfone
- CBNumber:CB82709840
- Molecular Formula:C7H5F2IO2S
- Formula Weight:318.08
- MOL File:802919-90-0.mol
DifluoroiodoMethyl phenyl sulfone Property
- Boiling point 312.4±42.0 °C(Predicted)
- Density 1.975±0.06 g/cm3(Predicted)
- storage temp. 2-8°C(protect from light)
Safety
- Safety Statements :24/25
- HS Code :29309090
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H315-H319-H335
- Precautionary statements P261-P305+P351+P338
DifluoroiodoMethyl phenyl sulfone Chemical Properties,Usage,Production
- Description A visible light-catalysed direct and regioselective (phenylsulfonyl) difluoromethylation of imidazo[1,2-A]pyridines and benzo[d]-imidazo[2,1-b]thiazoles was carried out by DifluoroiodoMethyl phenyl sulfone under mild conditions. This synthetic methodology enables the introduction of a CF2SO2Ph group in an efficient and regioselective reaction through C-H bond functionalization with a broad substrate scope in good to excellent yields.
- Uses Iododifluoromethyl phenyl sulfone can be used for the difluoromethylation of alkenes and alkynes initiated by triethylborane/air or arenediazonium salt/titanium chloride in moderate to good yields.
-
Reactions
(1) Difluoromethylation of terminal alkenes and alkynes.
-
References
[1] GUO-JIE YIN; W. F; Mei Zhu. Visible-light mediated regioselective (phenylsulfonyl)difluoromethylation of fused imidazoles with iododifluoromethyl phenyl sulfone[J]. Heterocyclic Communications, 2017. DOI:10.1515/hc-2017-0101.
[2] YA LI. Radical (Phenylsulfonyl)difluoromethylation with Iododifluoromethyl Phenyl Sulfone[J]. The Journal of Organic Chemistry, 2007. DOI:10.1021/jo070618s.
DifluoroiodoMethyl phenyl sulfone Preparation Products And Raw materials
Raw materials
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- 苯类
- C7H5F2IO2S
- (二氟碘甲基)磺酰]苯
- 二氟碘甲基苯基砜
- 802919-90-0
- Benzene, [(difluoroiodomethyl)sulfonyl]-
- (difluoroiodomethylsulfonyl)benzene
- DifluoroiodoMethyl phenyl sulfone