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ME0328

ME0328 Structure
ME0328
ME0328 Property
  • storage temp. Inert atmosphere,Store in freezer, under -20°C
  • solubility DMSO: soluble10mg/mL, clear
  • form powder
  • color white to beige
  • Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
  • UNSPSC Code 12352200
  • NACRES NA.77
Safety
  • Hazard Codes  :Xn
  • Risk Statements  :22-43
  • Safety Statements  :36/37
  • WGK Germany  :3
  • NFPA 704:
    0
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302
  • Precautionary statements P280-P305+P351+P338
ME0328 Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: SML0999
  • Product name : ME0328
  • Purity: ≥98% (HPLC)
  • Packaging: 5MG
  • Price: ₹14807.4
  • Updated: 2022/06/14
  • Buy: Buy

ME0328 Chemical Properties,Usage,Production

  • Description The poly(ADP-ribose) polymerases (PARPs) are enzymes with roles in DNA repair, apoptosis, inflammation, and other cellular events, particularly in response to reactive oxygen and nitrogen species. ME0328 is an inhibitor of PARP3 (IC50 = 0.89 μM), which is a regulator of DNA repair and mitotic progression. It displays selectivity for PARP3 over 12 other PARP family members. ME0328 is cell permeable and elicits PARP3-specific effects at submicromolar concentrations.
  • Uses ME0328 is a potent poly ADP ribose polymerase (PARP) inhibitor with selectivity towards the human ADP-Ribosyltransferase ARTD3/PARP3.
  • IC 50 ARTD3/PARP3: 0.89 μM (IC50); ARTD1/PARP1: 6.3 μM (IC50); ARTD2/PARP2: 10.8 μM (IC50); ARTD6/TNKS2: 34.3 μM (IC50); ARTD5/TNKS1: 47.3 μM (IC50); ARTD10/PARP10: 71.3 μM (IC50)
  • References 1) Lindgren?et al. (2013),?PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ART3/PARP3; ACS Chem. Biol.,8?1689
ME0328 Preparation Products And Raw materials
Raw materials
Preparation Products
ME0328 Suppliers
Global(115)Suppliers
  • Supplier：
    career henan chemical co
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  • Supplier：
    TargetMol Chemicals Inc.
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  • Email：support@targetmol.com
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ME0328 Spectrum
1445251-22-8, ME0328Related Search:
  • Inhibitors
  • 合成有机化合物配体
  • 抑制剂
  • 小分子抑制剂，天然产物
  • 化合物ME0328,10 MM DMSO 溶液
  • (S)-3-(4-氧代-3,4-二氢喹唑啉-2-基)-N-(1-苯乙基)丙酰胺
  • ME 0328,PARP-3抑制剂
  • (S)-3-(4-氧代-3,4-二氢喹唑啉-2-2)-N-1-苯乙基丙酰胺
  • 1445251-22-8
  • ME0328, 10 mM in DMSO
  • ME 0328, PARP-3 inhibitor
  • (S)-3-(4-Oxo-3,4-dihydroquinazolin-2-yl)-N-(1-phenylethyl)propanamide
  • ME0328 ME-0328
  • ME0328 USP/EP/BP
  • 2-Quinazolinepropanamide, 3,4-dihydro-4-oxo-N-[(1S)-1-phenylethyl]-
  • 4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide
  • 4-Dihydro-4-oxo-3
  • ME0328; ME 0328; ME-0328
  • (S)-3,4-Dihydro-4-oxo-N-(1-phenylethyl)-2-quinazolinepropanamide
  • 3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide
  • ME0328

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