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5-Bromo-2'-deoxycytidine

5-Bromo-2'-deoxycytidine Structure
5-Bromo-2'-deoxycytidine
  • CAS No.1022-79-3
  • Chemical Name:5-Bromo-2'-deoxycytidine
  • CBNumber:CB8261438
  • Molecular Formula:C9H12BrN3O4
  • Formula Weight:306.11
  • MOL File:1022-79-3.mol
5-Bromo-2'-deoxycytidine Property
  • Boiling point 510.8±60.0 °C(Predicted)
  • Density 2.12±0.1 g/cm3(Predicted)
  • RTECS HA3705000
  • storage temp. Store at 0°C
  • pka 14.03±0.60(Predicted)
  • form Powder
  • color White to Pale Yellow
  • CAS DataBase Reference 1022-79-3(CAS DataBase Reference)
  • FDA UNII 6M3TP1AIBH
Safety
  • Hazard Codes  :Xn
  • Risk Statements  :40
  • Safety Statements  :22-36
  • HS Code  :29389090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P305+P351+P338

5-Bromo-2'-deoxycytidine Chemical Properties,Usage,Production

  • Uses 5-Bromo-2'-deoxycytidine (BrdC) is a brominated derivative of the deoxyribonucleoside 2’-deoxycytidine. It induces DNA cross-linking and the formation of DNA strand breaks when incorporated into a DNA fragment in place of cytosine and exposed to UVB damage. BrdC inhibits cytopathogenicity induced by herpes simplex virus 1 (HSV-1) and HSV-2 in infected primary rabbit kidney (PRK) cells (MICs = 0.2-0.3 μg/ml). It decreases the survival of U-1 melanoma cells and AG1522 non-cancerous cells and induces sensitization of both to radiation. BrdC also sensitizes tumors to radiation and reduces tumor volume in a mouse model of glioma using RT-2 cells infused with an adenovirus expressing HSV thymidine kinase (ADV-TK) after implantation. In vivo, BrdC is converted to 5-bromo-2'-deoxyuridine (BrdU) and has been used to label cardiac progenitor cells (CPCs) in a rat model of myocardial infarction.
5-Bromo-2'-deoxycytidine Preparation Products And Raw materials
Raw materials
Preparation Products
5-Bromo-2'-deoxycytidine Suppliers
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5-Bromo-2'-deoxycytidine Spectrum
1022-79-3, 5-Bromo-2'-deoxycytidineRelated Search:
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  • C9H12BrN3O4
  • PERFEMIKER]5-溴-2'-脱氧胞苷,99%
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  • 1022-79-3
  • 5-Bromo-2''-deoxycytidine
  • 5-Bromo-2'-deoxycytidine
  • 4-amino-5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • 5-Bromo-2'-deoxycytidine USP/EP/BP
  • Cytidine, 5-bromo-2'-deoxy-
  • 5-Br-2'-dC
  • 5-Br-2'-deoxycytidine
  • 4-Amino-5-bromo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxy-methyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-on
  • 4-AMino-5-broMo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidin-2(1H)-one
  • 4-aMino-5-broMo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)oxolan-2-yl]-1,2-dihydropyriMidin-2-one
  • 5-Bromo-2'-deoxycytidine ,98%
  • Aids-072378
  • Aids072378
  • 5-Bromo-dcrd
  • 4-Amino-5-bromo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxy-methyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)
  • 4-Amino-1-(2-deoxy-β-D-ribofuranosyl)-5-bromopyrimidin-2(1H)-one
  • 4-Amino-5-bromo-1-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • 5-BROMO-2''-DEOXYCYTIDINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM
  • 5-BROMO-2''-DEOXYCYTIDINE crystalline
  • Bromodeoxycytidine
  • 5-BROMO-2''-DEOXYCYTIDINE(5-BRDC)
  • 5-Bromo-2'-deoxy-D-cytidine
  • 5-BROMODEOXYCYTIDINE
  • 5-BROMO-2'-DEOXYCYTIDINE MONOHYDRATE
  • 5-BR-DC
  • 2'-DEOXY-5-BROMOCYTIDINE
  • 5-bromo-2’-deoxy-cytidin

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