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(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID

(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID Structure
(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID
  • CAS No.77159-57-0
  • Chemical Name:(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID
  • CBNumber:CB8160902
  • Molecular Formula:C20H36O3
  • Formula Weight:324.5
  • MOL File:77159-57-0.mol
(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID Property
  • storage temp. Store at -20°C
  • solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P280-P301+P312-P302+P352-P305+P351+P338

(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID Chemical Properties,Usage,Production

  • Uses (±)15-HEDE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE. 15-HEDE is formed from eicosadienoic acid in macrophages. It inhibits 5-lipoxygenase (5-LO; IC50=35 μM).
  • Definition ChEBI: 15-HEDE is a hydroxyeicosadienoic acid that consists of 11Z,13E-eicosatrienoic acid bearing a 15-hydroxy substituent. It is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid. There are no reports in the literature of biological activity associated with 15-HEDE. It has a role as a metabolite.
  • References [1] Haviv, et al. Structural requirements for the inhibition of 5-lipoxygenase by 15-hydroxyeicosa-5,8,11,13-tetraenoic acid analogues. J. Med. Chem. 30(2), 254-263 (1987).
(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID Suppliers
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(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID Spectrum
77159-57-0, (+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACIDRelated Search:
  • 抑制剂
  • C20H36O3
  • (±)15-HEDE
  • 77159-57-0
  • 11,13-Eicosadienoic acid, 15-hydroxy-, (11Z,13E)-
  • ZTRWPEHMGCHTIT-QWAPPMFBSA-N
  • (+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID
  • (+/-)15-HEDE

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