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15(S)-HEDE

15(S)-HEDE Structure
15(S)-HEDE
  • CAS No.92693-04-4
  • Chemical Name:15(S)-HEDE
  • CBNumber:CB1733893
  • Molecular Formula:C20H36O3
  • Formula Weight:324.5
  • MOL File:92693-04-4.mol
15(S)-HEDE Property
  • Boiling point 475.0±18.0 °C(Predicted)
  • Density 0.958±0.06 g/cm3(Predicted)
  • storage temp. Store at -20°C
  • solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
  • pka 4.78±0.10(Predicted)
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements
  • Precautionary statements

15(S)-HEDE Chemical Properties,Usage,Production

  • Description 15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 μM.1
  • Uses 15(S)-HEDE (Compound 8) is an analogue of 15-HEDE (HY-121987A) that inhibits 5-lipoxygenase with an IC50 value of 26 μM. 15(S)-HEDE is promising for research of inflammatory disease[1].
  • References 1. Haviv, F., Ratajczyk, J.D., DeNet, R.W., et al. Structural requirements for the inhibition of 5-lipoxygenase by 15-hydroxyeicosa-5,8,11,13-tetraenoic acid analogues J. Med. Chem. 30(2),254-263(1987).
15(S)-HEDE Preparation Products And Raw materials
Raw materials
Preparation Products
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15(S)-HEDE Spectrum
92693-04-4, 15(S)-HEDERelated Search:
  • 药靶配体
  • 抑制剂
  • 92693-04-4
  • 11,13-Eicosadienoic acid, 15-hydroxy-, [S-(E,Z)]- (9CI)
  • 15(S)HEDE,15(S) HEDE
  • ZTRWPEHMGCHTIT-XMSPSUPSSA-N
  • 15S-HYDROXY-11Z,13E-EICOSADIENOIC ACID
  • 15(S)-HEDE
  • 15(S)-HYDROXYEICOSA-11Z,13E-DIENOIC ACID

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