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diphyllin

diphyllin Structure
diphyllin
  • CAS No.22055-22-7
  • Chemical Name:diphyllin
  • CBNumber:CB81346204
  • Molecular Formula:C21H16O7
  • Formula Weight:380.35
  • MOL File:22055-22-7.mol
diphyllin Property
  • Melting point 290℃ (methanol )
  • Boiling point 638.8±55.0 °C(Predicted)
  • Density 1.445±0.06 g/cm3 (20 ºC 760 Torr)
  • storage temp. 2-8°C
  • solubility Soluble in DMSO
  • pka 7.82±0.20(Predicted)
  • form powder
  • color white to light brown
  • FDA UNII W4PN5LDP26
  • UNSPSC Code 12352200
  • NACRES NA.77
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
diphyllin Price More Price(2)
  • Brand: Sigma-Aldrich(India)
  • Product number: SML1766
  • Product name : Diphyllin
  • Purity: ≥98% (HPLC)
  • Packaging: 5MG
  • Price: ₹11009.03
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: SML1766
  • Product name : Diphyllin
  • Purity: ≥98% (HPLC)
  • Packaging: 25MG
  • Price: ₹44566.53
  • Updated: 2022/06/14
  • Buy: Buy

diphyllin Chemical Properties,Usage,Production

  • Uses Diphyllin has been used to study its antibacterial and antibiofilm activities against fish pathogens.
  • Definition ChEBI: Diphyllin is a lignan.
  • General Description Diphyllin, a major glycoside compound, is a plant-derived lignan. It is present in Cleistanthus collinus.
  • Biochem/physiol Actions Diphyllin is a natural arylnaphthalene that exhibits potent anticancer and antiviral activities. It is a potent inhibitor of vacuolar H(+)-ATPase (V-ATPase) that inhibits lysosomal acidification in osteoclasts.
  • in vivo

    Diphyllin (20 mg/kg; oral; once a day; for 10 consecutive days) significantly inhibits the tumor growth of SGC7901 cells in mice, reduced tumor weight, downregulated the expression of V-ATPase in tumor tissues, and reduced the levels of MMP-2 and MMP-9 in serum[4].

  • IC 50 HIV-1: 0.38 μM (IC50); Vacuolar type H+-ATPase: 17 nM (IC50); Vesicular stomatitis virus (VSV)
diphyllin Preparation Products And Raw materials
Raw materials
Preparation Products
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diphyllin Spectrum
22055-22-7, diphyllinRelated Search:
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  • 22055-22-7
  • Diphyllin, 10 mM in DMSO
  • 9-(Benzo[d][1,3]dioxol-5-yl)-4-hydroxy-6,7-dimethoxynaphtho[2,3-c]furan-1(3H)-one
  • Benz[f]isobenzofuran-1(3H)-one,9-(1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-
  • Naphtho[2,3-c]furan-1(3H)-one, 9-(1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-
  • Phyllis
  • 9-(1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-3H-benzo[f][2]benzofuran-1-one
  • Diphyllin >=98% (HPLC)
  • NSC 309691
  • Diphyllin【naphthofuran】
  • 9-(1,3-Benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxynaphtho[2,3-c]furan-1(3H)-one
  • 4-Hydroxy-6,7-dimethoxy-9-(1,3-benzodioxole-5-yl)-1,3-dihydronaphtho[2,3-c]furan-1-one

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