ChemicalBook > CAS DataBase List > justicidin A
justicidin A
justicidin A
- CAS No.25001-57-4
- Chemical Name:justicidin A
- CBNumber:CB91359285
- Molecular Formula:C22H18O7
- Formula Weight:394.37
- MOL File:25001-57-4.mol
justicidin A Property
- Melting point 263°
- Boiling point 644.5±55.0 °C(Predicted)
- Density 1.366±0.06 g/cm3(Predicted)
- form Solid
- color White to off-white
- FDA UNII Q58EXN1G4M
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
justicidin A Chemical Properties,Usage,Production
- Uses justicidin A is a nature product that could be isolated form Justicia procumbens. justicidin A decreases the level of Ku70 leading to translocation of Bax from the cytosol to mitochondria to induce apoptosis. justicidin A can be used in research of cancer[1].
- Definition ChEBI: Justicidin A is a lignan.
-
in vivo
justicidin A (6.2 mg/kg; p.o.; daily, for 56 days) suppresses the growth of human colorectal cancer cells in mice[1].
Animal Model: NOD-SCID mice with HT-29 cells xenograftes[1] Dosage: 6.2 mg/kg Administration: Oral administration; daily, for 56 days Result: Inhibited tumor growth and decreased tumor weight.
justicidin A Preparation Products And Raw materials
Raw materials
Preparation Products
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25001-57-4, justicidin ARelated Search:
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- justicidin A