ChemicalBook > CAS DataBase List > Azidoacetic acid methyl ester
Azidoacetic acid methyl ester
Azidoacetic acid methyl ester
- CAS No.1816-92-8
- Chemical Name:Azidoacetic acid methyl ester
- CBNumber:CB81105186
- Molecular Formula:C3H5N3O2
- Formula Weight:115.0907
- MOL File:1816-92-8.mol
Azidoacetic acid methyl ester Property
- Boiling point 35 °C
- Density 1.182 g/mL at 25 °C
- refractive index n20/D1.440
- Flash point 48℃
- form liquid
- UNSPSC Code 12352100
- NACRES NA.22
Safety
- Hazard Codes :Xi
- Risk Statements :5-10-36/37/38
- Safety Statements :26
- RIDADR :UN 1993C 3 / PGIII
- WGK Germany :3
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H226-H315-H319-H335
- Precautionary statements P261-P305+P351+P338
Azidoacetic acid methyl ester Chemical Properties,Usage,Production
-
Uses
- Methyl 2-azidoacetate is widely used as a precursor to build triazole derivatives via alkyne-azide click chemistry. Some of the examples include the synthesis of coumarin-triazole derivatives as potential antiplasmodial agents and macrocyclic triazole containing largazole analogs as histone deacetylases-1 (HDAC1) inhibitors.
- It can be used to synthesize various pyrrole derivatives by Knoevenagel condensation as in the synthesis of near-infrared boron dipyrromethene (BODIPY) donors for organic tandem solar cells.
- It can also be used in Hemetsberger-Knittel synthesis of substituted 5-, 6-, and 7-azaindoles.
- Synthesis of highly fluorescent pyreno[2,1-b]pyrroles using methyl 2-azidoacetate as one of the reagents.
Azidoacetic acid methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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