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(S)-(-)-WARFARIN

(S)-(-)-WARFARIN Structure
(S)-(-)-WARFARIN
  • CAS No.5543-57-7
  • Chemical Name:(S)-(-)-WARFARIN
  • CBNumber:CB7267099
  • Molecular Formula:C19H16O4
  • Formula Weight:308.33
  • MOL File:5543-57-7.mol
(S)-(-)-WARFARIN Property
  • Melting point ≥170 °C
  • storage temp. 2-8°C
  • solubility DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 5 mg/ml
  • form A crystalline solid
  • color white to pale yellow
  • CAS DataBase Reference 5543-57-7(CAS DataBase Reference)
  • FDA UNII HP31W7FNP4
  • UNSPSC Code 12161501
  • NACRES NA.77
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H300+H310+H330-H360D-H372-H411
  • Precautionary statements P202-P264-P273-P280-P302+P352+P310-P304+P340+P310
(S)-(-)-WARFARIN Price More Price(2)
  • Brand: Sigma-Aldrich(India)
  • Product number: UC214
  • Product name : (S)-(−)-Warfarin
  • Purity: ≥97% (HPLC)
  • Packaging: 5MG
  • Price: ₹85052.03
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: UC214
  • Product name : (S)-(−)-Warfarin
  • Purity: ≥97% (HPLC)
  • Packaging: 10MG
  • Price: ₹151614.95
  • Updated: 2022/06/14
  • Buy: Buy

(S)-(-)-WARFARIN Chemical Properties,Usage,Production

  • Description (–)-Warfarin is a component of (±)-warfarin . It is an anticoagulant that interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting cascade proteins, inhibiting the initiation of clotting. In vivo, (–)-warfarin slows formation of the prothrombin complex and exhibits 6.6-fold more potent anticoagulant activity than (+)-warfarin in rats. (–)-Warfarin is primarily metabolized by the cytochrome P450 (CYP) isoform CYP2C9 and genetic polymorphisms in this enyzme, as well as other compounds metabolized by CYP2C9, increase the potential for catastrophic bleeding complications. Formulations containing warfarin have been used to treat and prevent blood clots in atrial fibrillation, heart valve replacement, venous thrombosis, and pulmonary embolism.
  • Chemical Properties White Solid
  • Uses The S-(-)-form of Warfarin (W498500). Coumarin anticoagulant.
  • Uses (S)-(?)-Warfarin has been used in cell cultures.
  • Definition ChEBI: (S)-warfarin is a 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one that has (S)-configuration (the racemate is warfarin, an anticoagulant drug and rodenticide). It is a conjugate acid of a (S)-warfarin(1-). It is an enantiomer of a (R)-warfarin.
  • General Description Warfarin is an antagonist of vitamin K. It is an oral coumarin anticoagulant.
  • Biochem/physiol Actions Warfarin is used to regulate and inhibit thromboembolic disorders. The CYP2C9 (cytochrome P450 family 2 subfamily C member 9)?protein plays a major role in the inactivation of potent S-warfarin.
(S)-(-)-WARFARIN Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-(-)-WARFARIN Suppliers
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(S)-(-)-WARFARIN Spectrum
5543-57-7, (S)-(-)-WARFARINRelated Search:
  • Heterocycles
  • Chiral Reagents
  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • 杂质对照品
  • 抑制剂
  • C19H16O4
  • 华法林杂质17
  • 化合物 (S)-WARFARIN
  • 华法林钠杂质23((S)-华法林)
  • 华法林杂质17(华法林 S异构体)
  • 化合物 T19708
  • (S)-(-)-华法令
  • (-)-WARFARIN
  • S-(-)-华法林
  • 华法林S异构体杂质
  • 薄血丸
  • S-文拉法辛
  • 5543-57-7
  • S-(?)-Warfarin &gt,99
  • Warfarin sodium Impurity 23 ((S)-Warfarin)
  • S-(-)-WarfarinQ: What is S-(-)-Warfarin Q: What is the CAS Number of S-(-)-Warfarin Q: What is the storage condition of S-(-)-Warfarin Q: What are the applications of S-(-)-Warfarin
  • Warfarin Impurity 17
  • Warfarin Impurity 17（Warfarin S-Isomer）
  • Warfarin S-Isomer
  • 2-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-4-one
  • 2H-1-Benzopyran-2-one, 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]- (9CI)
  • 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, (S)-
  • s-(-)-3-acetonybenzyl)-4-hydroxycoumarin
  • 4-HYDROXY-3-((S)-3-OXO-1-PHENYL-BUTYL)-CHROMEN-2-ONE
  • (S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
  • Warfarin,R-
  • (S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
  • S-(-)-3-(ACETONYLBENZYL)-4-HYDROXYCOUMARIN
  • (S)-(+)-4-HYDROXY-3-(3-OXO-1-PHENYLBUTYL)-2H-1-BENZOPYRAN-2-ONE
  • S-(-)-4-HYDROXY-3-(3-OXO-1-PHENYBUTYL)-2H-1-BENZOPYRAN-2-ONE
  • (S)-(+)-4-HYDROXY-3-(3-OXO-1-PHENYBUTYL)-2H-1-BENZOPYRAN-2-ONE
  • (S)-WARFARIN
  • (S)-(-)-WARFARIN
  • 4-Hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one
  • 2-hydroxy-3-(3-keto-1-phenyl-butyl)chromone
  • (-)-4-Hydroxy-3-[(S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one
  • (-)-3-[(S)-α-Acetonylbenzyl]-4-hydroxycoumarin
  • (-)-3-[(S)-1-Phenyl-3-oxobutyl]-4-hydroxycoumarin
  • S-(-)-3-Acetonybenzyl)-4-hydroxycoumarin, S-(-)-4-Hydroxy-3-(3-oxo-1-phenybutyl)-2H-1-benzopyran-2-one
  • 4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-chromen-2-one
  • Coumarin, 3-(a-acetonylbenzyl)-4-hydroxy-, (S)-(-)- (8CI)

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