ChemicalBook > CAS DataBase List > KIGAMICIN C
KIGAMICIN C
- CAS No.680571-51-1
- Chemical Name:KIGAMICIN C
- CBNumber:CB72453298
- Molecular Formula:C41H47NO16
- Formula Weight:809.81
- MOL File:680571-51-1.mol
KIGAMICIN C Property
- storage temp. Store at -20°C
- solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
- form Yellow powder.
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
KIGAMICIN C Chemical Properties,Usage,Production
- Uses Kigamicin C is a novel antibiotic antiproliferative with novel action.
- Uses Kigamicin C was discovered by an anti-austerity strategy, targeting cancer cells' tolerance to starvation. It selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions. The mechanism of action is proposed to be via blockade of aPKB/Akt activation, caused by the withdrawal of nutrients. It is active in vivo against a human pancreatic cancer xenograft model. Kigamicin C also inhibits the growth of Gram positive bacteria including MRSA, but is not active against Gram negative bacteria.
KIGAMICIN C Preparation Products And Raw materials
Raw materials
Preparation Products
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680571-51-1, KIGAMICIN CRelated Search:
- 21-hydroxyoligomycin A anguinomycin A Hexacyclinic acid KAZUSAMYCIN A FROM STREPTOMYCES SP. echinosporin Daunorubicin hydrochloride PD 124895 Cladospirone bisepoxide Cochliodinol,fromChaetomiumglobosum. 6H-Benzo(d)naphtho(1,2-b)pyran-6-one, 4-(6-deoxy-alpha-galactofuranosy l)-1-hydroxy-10,12-dimethoxy-8-methyl- Maltoryzine KIGAMICIN C 3',4'-DIMETHOXYBIPHENYL-3-CARBALDEHYDE 2,5-DIHYDROXY-4'-METHYLBIPHENYL 1-(2-HYDROXY-5-METHOXY-4-METHYL-PHENYL)-ETHANONE 7-METHYL-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 4-hydroxy-5-methoxy-1,1'-biphenyl-3-carbaldehyde 8-HYDROXY-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE
- 抑制剂
- 微生物代谢物
- C41H47NO16
- 克加霉素C
- 木贺霉素 C
- 680571-51-1
- Oxazolo[3,2-b]xantheno[4',3',2':4,5][1,3]benzodioxino[7,6-g]isoquinoline-16,19-dione, 3-[[(2S,5S,6R)-5-[(2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-1,2,3,4,8a,9,11,11a,13,14-decahydro-1,4,17,18-tetrahydroxy-11a-methyl-, (1S,3R,4S,8aR,11aR)-
- KIGAMICIN C
