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BREVETOXIN B

BREVETOXIN B Structure
BREVETOXIN B
  • CAS No.79580-28-2
  • Chemical Name:BREVETOXIN B
  • CBNumber:CB7161922
  • Molecular Formula:C50H70O14
  • Formula Weight:895.08
  • MOL File:79580-28-2.mol
BREVETOXIN B Property
  • Melting point 270(Disassembly)
  • Density 1.188±0.06 g/cm3(Predicted)
  • storage temp. −20°C
  • solubility Ethyl Acetate: soluble
  • form A film
  • pka 13.72±0.70(Predicted)
  • color tan to white
  • optical activity +154.022 (CHCl3)
  • Water Solubility ethyl acetate: soluble
    methanol: soluble
    water: soluble
  • FDA UNII 8WBN7K7T6Z
  • UNSPSC Code 51111800
  • NACRES NA.77
Safety
  • Hazard Codes  :T+
  • Risk Statements  :26/27/28
  • Safety Statements  :22-36/37/39-45
  • RIDADR  :UN 2811 6.1/PG 2
  • WGK Germany  :3
  • RTECS  :XW5886000
  • HazardClass  :6.1(a)
  • PackingGroup  :I
  • NFPA 704:
    0
    4 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H300+H310+H330
  • Precautionary statements P260-P262-P264-P280-P302+P352+P310-P304+P340+P310
BREVETOXIN B Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: 203732
  • Product name : Brevetoxin PbTx-2, Ptychodiscus brevis - CAS 79580-28-2 - Calbiochem
  • Purity: Lipid-soluble polyether neurotoxin that binds to Na+ channels on nerves and muscles causing an excessive influx of Na+ across membranes.
  • Packaging: 100μG
  • Price: ₹50790
  • Updated: 2022/06/14
  • Buy: Buy

BREVETOXIN B Chemical Properties,Usage,Production

  • Description Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. Brevetoxin B is ichthyotoxic at nanomolar concentrations and is responsible for an illness described as neurotoxic shellfish poisoning.
  • Uses Brevetoxin B (Brevetoxin-2; PbTx-2) is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. Brevetoxin B binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50=15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively.
  • Definition ChEBI: Brevetoxin B is a ciguatoxin.
BREVETOXIN B Preparation Products And Raw materials
Raw materials
Preparation Products
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BREVETOXIN B Spectrum
79580-28-2, BREVETOXIN BRelated Search:
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  • Monovalent Ion Channels
  • Ion Channels
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  • BioChemical
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