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Nonaethylene Glycol Monomethyl Ether

Nonaethylene Glycol Monomethyl Ether Property

Melting point 14 °C
Boiling point 170 °C(Press: 0.01 Torr)
Density 1.10
refractive index 1.4570 to 1.4620
pka 14.36±0.10(Predicted)
form clear liquid
color Colorless to Light yellow to Light orange
InChI InChI=1S/C19H40O10/c1-21-4-5-23-8-9-25-12-13-27-16-17-29-19-18-28-15-14-26-11-10-24-7-6-22-3-2-20/h20H,2-19H2,1H3
InChIKey VVHAVLIDQNWEKF-UHFFFAOYSA-N
SMILES C(O)COCCOCCOCCOCCOCCOCCOCCOCCOC

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Hazard and Precautionary Statements (GHS)

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Nonaethylene Glycol Monomethyl Ether Chemical Properties,Usage,Production

Description m-PEG9-alcohol is a PEG linker containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses Nonaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Definition ChEBI: Nonaethylene glycol monomethyl ether is nonaethylene glycol in which one of the hydroxy groups is substituted by methoxy. It is functionally related to a nonaethylene glycol.
in vitro Nonaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used to synthesize PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase, and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
IC 50 PEGs
References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Nonaethylene Glycol Monomethyl Ether Preparation Products And Raw materials

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Nonaethylene Glycol Monomethyl Ether Spectrum

6048-68-6, Nonaethylene Glycol Monomethyl Ether Related Search:

peg
Monofunctional Ethylene Glycols
Ethylene Glycols & Monofunctional Ethylene Glycols
化工中间体
抑制剂
PEG系列产品-m-PEG系列
生化试剂
醇类
助剂
单甲醚
聚乙二醇修饰剂
Monofunctional Ethylene Glycols
Ethylene Glycols & Monofunctional Ethylene Glycols
C19H40O10
化合物 NONAETHYLENE GLYCOL MONOMETHYL ETHER
甲基-PEG9-羟基
甲基-九聚乙二醇-羟基
甲氧基-九聚乙二醇
2,5,8,11,14,17,20,23,26-九氧杂-28-二十八醇
九乙二醇单甲醚
九聚乙二醇单甲醚
九甘醇单甲醚
壬乙二醇单甲醚
2,5,8,11,14,17,20,23,26-九氧杂二十八烷-28-醇
甲基-九聚乙二醇
6048-68-6
mPEG9-OH/3,6,9,12,15,18,21,24,27-Nonaoxaoctacosan-1-ol
HO-(CH2CH2O)9-Me
3,6,9,12,15,18,21,24,27-Nonaoxaoctacosan-1-ol
NonaethyleneGlycolMonomethylEther&gt
2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
2,5,8,11,14,17,20,23,26-Nonaoxa-28-octacosanol
O-metil-nonaetilenglicol
Methyl-PEG9-alcohol
m-PEG9-alcohol
2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-ol
MPEG-9
MPEG9-OH
NONAETHYLENE GLYCOL MONOMETHYL ETHER