Description
Ginkgolide C is a flavone first extracted from
G. biloba leaves with multiple reported biological functions. It has been identified as a selective platelet activating factor receptor antagonist (IC
50 = 37.6 μM). Ginkgolide C has also been shown to increase lipolysis and to inhibit adipogenesis in adipocytes
via the activated AMPK pathway.
Chemical Properties
Crystalline Solid
Uses
Family of bioactive terpenes treating cardiovascular and cerebrovascular diseases. Specific platelet activating factor (PAF) antagonists.
Uses
Reference compound for PAF receptors in biological systems.
IC 50
AMPK; MMP-9; Sirtuin
References
[1] PIERRE BRAQUET. Recent progress in ginkgolide research[J]. Medicinal Research Reviews, 1991, 11 3: 295-355. DOI:
10.1002/med.2610110303[2] CHIAN-JIUN LIOU. Ginkgolide C Suppresses Adipogenesis in 3T3-L1 Adipocytes via the AMPK Signaling Pathway.[J]. Evidence-based Complementary and Alternative Medicine, 2015: 298635. DOI:
10.1155/2015/298635
