Uses
(S)-(-)-5-Fluorowillardiine is a potent and selective AMPA receptor agonist at hGluR1 and hGluR2 (1,2).
Definition
ChEBI: An alanine derivative that is L-alanine bearing a 5-fluorouracil-1-yl substituent at position 3. A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (Ki = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and
hGluR5 respectively).
Biological Activity
A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (K i = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively). Also available as part of the AMPA Receptor Tocriset™ .
