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L-759,633

L-759,633 Structure
L-759,633
  • CAS No.174627-50-0
  • Chemical Name:L-759,633
  • CBNumber:CB6837204
  • Molecular Formula:C26H40O2
  • Formula Weight:384.59
  • MOL File:174627-50-0.mol
L-759,633 Property
  • Boiling point 447.9±45.0 °C(Predicted)
  • Density 0.956±0.06 g/cm3(Predicted)
  • storage temp. Store at +4°C
  • solubility Ethanol:20.0(Max Conc. mg/mL);52.0(Max Conc. mM)
    PBS (pH 7.2):0.25(Max Conc. mg/mL);0.65(Max Conc. mM)
  • form Liquid
  • color Colorless to light yellow
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H225-H319-H336
  • Precautionary statements P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501

L-759,633 Chemical Properties,Usage,Production

  • Description L-759,633 is a high-affinity peripheral cannabinoid receptor (CB2)-selective agonist with Ki values of 6.4 and 1,043 nM for CB2 and central cannabinoid (CB1) receptors, respectively. L-759,633 inhibits forskolin-stimulated cyclic AMP production in CHO cells transfected with CB2 or CB1 receptors with IC50 values of 8.1 nM and 10 μM, respectively.
  • Uses L 759633 is a cannabinoid receptor (CB2) selective agonist and a structural analogues of ??9-Tetrahydro Cannabinol, an active constituent of cannabis. L 759633 has analgesic and anti-inflammatory properties.
  • Definition ChEBI: 6h-dibenzo[b,d]pyran, 3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-, (6ar,10ar)- is a 1-benzopyran.
  • Biological Activity High affinity, selective CB 2 receptor agonist (K i values are 6.4 and 1043 nM for CB 2 and CB 1 receptors respectively). Potently inhibits forskolin-stimulated cAMP production via CB 2 receptors expressed in CHO cells (EC 50 = 8.1 nM).
  • IC 50 CB2: 6.4 nM (Ki); CB1: 1043 nM (Ki)
L-759,633 Preparation Products And Raw materials
Raw materials
Preparation Products
L-759,633 Suppliers
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L-759,633 Spectrum
174627-50-0, L-759,633Related Search:
  • Cannabinoid receptor
  • C26H40O2
  • 化合物 T27778
  • 174627-50-0
  • L759633,L-759633
  • L-759
  • L 759
  • 6H-Dibenzo[b,d]pyran, 3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-, (6aR,10aR)-
  • (6aR,10aR)-1-methoxy-6,6,9-trimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene
  • (6aR,10aR)-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-6H-dibenzo[b,d]pyran
  • L-759,633

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