ChemicalBook > CAS DataBase List > (6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN

(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN

(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN Structure
(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN
  • CAS No.259869-55-1
  • Chemical Name:(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN
  • CBNumber:CB6332673
  • Molecular Formula:C22H32O
  • Formula Weight:312.49
  • MOL File:259869-55-1.mol
(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN Property
  • Boiling point 382.0±42.0 °C(Predicted)
  • Density 0.950±0.06 g/cm3(Predicted)
  • storage temp. −20°C
  • solubility Chloroform, Ethyl Acetate
  • form Oil
  • color Clear Colorless
  • FDA UNII TDG8048RDA
  • UNSPSC Code 12352200
  • NACRES NA.77
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN Chemical Properties,Usage,Production

  • Uses JW 133 is an intermediate used to synthesize potent CB2-Selective Cannabinoid Receptor Ligands such as 4-oxo-1,4-dihydroquinoline-3-carboxamides and 3-(1'',1''-Dimethylbutyl)-1-deoxy-Δ8-THC analogs.
  • Definition ChEBI: JWH-133 is a dibenzopyran that is Delta(9)-tetrahydrocannabinol which is lacking the hydroxy group and in which the pentyl group at position 3 has been replaced by a 1,1-dimethylbutyl group. A potent and highly selective CB2 receptor agonist. It has a role as a CB2 receptor agonist, an antineoplastic agent, a vasodilator agent, an anti-inflammatory agent, an apoptosis inhibitor, an analgesic and an opioid analgesic. It is a dibenzopyran, an organic heterotricyclic compound and a benzochromene.
  • Biological Activity Potent CB 2 selective agonist (K i = 3.4 nM). Approx. 200-fold selective over CB 1 receptors. Active in vivo , reducing spasticity in a murine model of multiple sclerosis. Also available in water soluble emulsion ((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran ).
  • storage Store at -20°C
(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN Preparation Products And Raw materials
Raw materials
Preparation Products
(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN Suppliers
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(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN Spectrum
259869-55-1, (6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRANRelated Search:
  • Cannabinoids
  • Cannabinoid receptor
  • 对照品
  • 细胞生物学试剂
  • 抑制剂
  • C22H32O
  • (6AR,10AR)-3-(1,1-二甲基丁基)-6A,7,10,10A-四氢-6,6,9-三甲基-6H-二苯并[B,D]吡喃
  • 259869-55-1
  • JWH 133
  • CS-317
  • (6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene
  • (6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene
  • JW 133 (10 mg/mL in Methyl Acetate)
  • JWH 133 (in Tocrisolve 100)
  • JWH 133 (in Tocrisolve(TM) 100)
  • JW 133
  • 3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-THC, 3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-tetrahydrocannabinol
  • (6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-(6H)-dibenzo[b.d]pyrane
  • JWH 133, >=98%
  • 3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-THC
  • 3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-tetrahydrocannabinol
  • 6H-Dibenzo[b,d]pyran, 3-(1,1-diMethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-triMethyl-, (6aR,10aR)-
  • (6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN

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