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CYTOCHALASIN A

CYTOCHALASIN A Structure
CYTOCHALASIN A
  • CAS No.14110-64-6
  • Chemical Name:CYTOCHALASIN A
  • CBNumber:CB6735221
  • Molecular Formula:C29H35NO5
  • Formula Weight:477.59
  • MOL File:14110-64-6.mol
CYTOCHALASIN A Property
  • Melting point 190-191 °C
  • Boiling point 725.1±60.0 °C(Predicted)
  • Density 1.20±0.1 g/cm3(Predicted)
  • storage temp. -20°C
  • solubility ethanol: 20 mg/mL, clear, colorless
  • pka 13.54±0.70(Predicted)
  • form Powder
  • color White
  • Water Solubility Soluble in DMF, DMSO, ethanol and acetone. Insoluble in water.
  • Sensitive Light Sensitive
  • BRN 949521
  • LogP 1.849 (est)
  • FDA UNII BV8WQ9500E
  • EPA Substance Registry System Cytochalasin A (14110-64-6)
  • UNSPSC Code 12352200
  • NACRES NA.77
Safety
  • Hazard Codes  :T+,T
  • Risk Statements  :26/27/28-63
  • Safety Statements  :28-36/37-45
  • RIDADR  :UN 1544 6.1/PG 2
  • WGK Germany  :3
  • F  :10
  • HazardClass  :6.1(a)
  • PackingGroup  :I
  • HS Code  :29349990
  • NFPA 704:
    0
    4 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H300+H310+H330-H361
  • Precautionary statements P201-P202-P260-P280-P302+P352+P310-P304+P340+P310
CYTOCHALASIN A Price More Price(3)
  • Brand: Sigma-Aldrich(India)
  • Product number: C6637
  • Product name : Cytochalasin A from Drechslera dematioidea
  • Purity: 
  • Packaging: 1MG
  • Price: ₹14267.35
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: ottokemi
  • Product number:  C 3040
  • Product name : Cytochalasin A, from drechslera dematioidea
  • Purity: 99%
  • Packaging: 1mg
  • Price: ₹13005
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ottokemi
  • Product number:  C 3040
  • Product name : Cytochalasin A, from drechslera dematioidea
  • Purity: 99%
  • Packaging: 10mg
  • Price: ₹110079
  • Updated: 2022/05/26
  • Buy: Buy

CYTOCHALASIN A Chemical Properties,Usage,Production

  • Description The cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin A is an oxidized analog of cytochalasin B which uniquely inhibits HIV-1 protease (IC50 = 3 μM). Cytochalasins A and B differ from other cytochalasins in being able to rapidly and reversibly inhibit glucose transport by competitively binding glucose transporters (Ki = 4.0 and 0.6 μM, respectively). Cytochalasin A also induces the phosphorylation of the tyrosine phosphatase PTP3 of Dictyostelium, activating STATc.
  • Chemical Properties white powder
  • Uses Cytochalasin A binds to the glucose transporter and inhibit monosaccharide transport across the plasma membrane. Preventing growth and sugar uptake in a Saccharomyces strain.
  • Uses Cytochalasin A is one of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, giving rise to pronounced morphogenic activity in animals and plants. Like most cytochalsins, cytochalasin A exhibits potent inhibition of actin filament function leading to cell death by apoptosis, and displays a broad range of resultant cellular actions. Despite the common mode of action, there is evidence that individual members of the class display diverse selectivity. Specifically, cytochalasin A is one of the few cytochalasins exhibiting activity against HIV-1 protease.
  • Definition ChEBI: Cytochalasin A is a cytochalasin.
  • Biochem/physiol Actions Cytochalasin A reacts with sulfhydryls, and inhibits growth and glucose transport in Saccharomyces. Cytochalasin A is an oxidizing analog of cytochalsin B.
CYTOCHALASIN A Preparation Products And Raw materials
Raw materials
Preparation Products
CYTOCHALASIN A Suppliers
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CYTOCHALASIN A Spectrum
14110-64-6, CYTOCHALASIN ARelated Search:
  • Toxins and Venoms
  • Mold
  • Cytoskeleton and Extracellular Matrix
  • antibiotic
  • Cell Signaling and Neuroscience
  • Actin Inhibitors and ProbesCell Signaling and Neuroscience
  • 抑制剂
  • 化工原料
  • 生化试剂
  • 植物提取物
  • 微生物代谢物
  • 其他生化试剂
  • Actin Inhibitors and Probes
  • BioChemical
  • Biochemicals and Reagents
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Enzyme Inhibitors by Type
  • Enzyme Inhibitors
  • Enzymes, Inhibitors, and Substrates
  • Cytoskeleton and Extracellular Matrix
  • Other
  • C29H35NO5
  • 松胞菌素A
  • 细胞松弛素A(>98%,BR)
  • 细胞松弛素 A 来源于长蠕孢菌
  • 细胞松弛素 A 来源于DRECHSLERA DEMATIOIDEA
  • 细胞松驰素A
  • 细胞分裂抑素A
  • 松胞素A
  • 细胞松弛素A
  • 细胞松驰素 A
  • 14110-64-6
  • Cytochalasin A from <i>Drechslera dematioidea</i>
  • CytochalasinA from Drechslera dematioidea
  • CYTOCHALASIN A(RG)
  • cytochalasin a from helminthosporium dematioideum
  • CYTOCHALASIN A
  • CYTOCHALASIN A FROM DRESCHSLERA DEMATIOIDEA, BIOCHEMIKA, >= 99.0% (TLC)
  • CYTOCHALASIN A FROM DRESCHSLERA DEMATIOIDEA
  • 2H-Oxacyclotetradecino2,3-disoindole-2,5,18-trione, 6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-, (3E,9R,11E,12aS,13S,15S,15aS,16S,18aS)-
  • 7(S)-hydroxy-16(R)-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13(E),21(E)-triene-1,20,23-trione
  • Cytochalasin A 5-Dehydrophomin Dehydrophomin
  • Cytochalasin dreschslera dematioidea
  • Dehydrophomin
  • 5,5-Didehydrophomin
  • (7S,13E,16R,21E)-7-Hydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13,21-triene-1,20,23-trione

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