Uses
[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) is a modified fragment of calcium/calmodulin-dependent protein kinase II that contains the active domain of CaMKII and has an alanine substitution at position 286. [Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) can be used to develop more potent CaMKII inhibitors[1].
References
[1] Ishida A, et al. Critical amino acid residues of AIP, a highly specific inhibitory peptide of calmodulin‐dependent protein kinase II[J]. FEBS letters, 1998, 427(1): 115-118. DOI:
10.1016/s0014-5793(98)00405-0