4-Chlorochalcone

Uses

4-Chlorochalcone belongs to the ketone derivative class and can be used as a pharmaceutical synthesis intermediate.

Uses

4-Chlorochalcone is a chalcone derivative. Its crystals exhibit monoclinic system with space group P2₁/c. It can undergo conjugate addition reaction with pyrrole in the presence of AlKIT-5 (mesoporous 3D aluminosilicate catalyst) to form the corresponding C2-alkylated pyrrole derivatives.

Definition

ChEBI: A member of the class of chalcones that is trans-chalcone substituted by a chloro group at position 4.

Synthesis Reference(s)

Tetrahedron Letters, 28, p. 4541, 1987 DOI: 10.1016/S0040-4039(00)96558-4

General Description

4-Chlorochalcone is a chalcone derivative. Its crystals exhibit monoclinic system with space group P2₁/c. It can undergo conjugate addition reaction with pyrrole in the presence of AlKIT-5 (mesoporous 3D aluminosilicate catalyst) to form the corresponding C2-alkylated pyrrole derivatives.