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iopydol
iopydol
- CAS No.5579-92-0
- Chemical Name:iopydol
- CBNumber:CB5941333
- Molecular Formula:C8H9I2NO3
- Formula Weight:420.97
- MOL File:5579-92-0.mol
iopydol Property
- Melting point 161°
- FDA UNII T4661K682A
- ATC code V08AD02
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
iopydol Chemical Properties,Usage,Production
- Originator Hytrast Vial,Guerbet
- Uses Iopydol is the X-ray contrast reagent.
- Uses Diagnostic aid (radiopaque medium, bronchographic) .
- Definition ChEBI: Iopydol is a chloropyridine.
-
Manufacturing Process
50 g 4-pyridone was dissolved in 300 ml 20% hydrochloric acid and slowly
mixed with 180 g of chloroiodide in 200 ml 20% hydrochloric acid. Then the
obtained dark solution was strong alkalized with sodium hydroxide. The
solvent was removed to dryness and sodium salt diiod-4-pyridone was
obtained. It was dissolved in water, filtered and equivalent quantity of glacial acetic acid or hydrochloric acid was added to give 3,5-diiod-4-pyridone as a powder. 34.5 g 3,5-diiod-pyridone was dissolved in 100 ml 1 N NaOH by heating on a water bath and added to a 15 g of monochlorohydrine added. The mixture was heated on water bath before a dense pasty mass obtained. It was filtered off and treated with 1 N NaOH. The obtained 1-(2,3- dihydroxypropyl)-3,5-diiodo-4(1H)-pyridinone was recrystallized from diluted hydrochloric acid. MP: 161°C. - Therapeutic Function Diagnostic aid
iopydol Preparation Products And Raw materials
Raw materials
Preparation Products
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5579-92-0, iopydolRelated Search:
- 小分子药物
- C8H9I2NO3
- 化合物 T32181
- 碘吡多
- 5579-92-0
- Jopydolum
- Iopydolum
- Iopidolo
- EINECS 226-968-6
- 4(1H)-Pyridinone, 1-(2,3-dihydroxypropyl)-3,5-diiodo-
- 1-(2,3-dihydroxy-propyl)-3,5-diiodo-1H-pyridin-4-one
- iopydol
- 1-glyceryl-3,5-diiodo-4-pyridone
- 1-(2,3-dihydroxypropyl)-3,5-diiodopyridin-4-one
- 1-(2,3-dihydroxypropyl)-3,5-diiodo-pyridin-4-one
- Iopidol
- 1-(2,3-Dihydroxypropyl)-3,5-diiodo-4(1H)-pyridone
- 1-(2,3-Dihydroxypropyl)-3,5-diiodo-4(1H)-pyridinone