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Crocetin

Crocetin Structure
Crocetin
  • CAS No.27876-94-4
  • Chemical Name:Crocetin
  • CBNumber:CB5780370
  • Molecular Formula:C20H24O4
  • Formula Weight:328.4
  • MOL File:27876-94-4.mol
Crocetin Property
  • Melting point 285°
  • Boiling point 386.14°C (rough estimate)
  • Density 1.0786 (rough estimate)
  • refractive index 1.4434 (estimate)
  • FEMA 2998 | SAFFRON (CROCUS SATIVUS L.)
  • storage temp. Inert atmosphere,Store in freezer, under -20°C
  • solubility DMSO (Slightly, Heated), Methanol (Slightly)
  • form Solid
  • pka 4.39±0.19(Predicted)
  • color Red to Very Dark Red
  • Stability Light Sensitive
  • LogP 4.312 (est)
  • FDA UNII 20TC155L9C
  • UNSPSC Code 12352200
  • NACRES NA.77
Safety
  • HS Code  :29171900
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H317
  • Precautionary statements P261-P264-P270-P280-P301+P312-P302+P352

Crocetin Chemical Properties,Usage,Production

  • Chemical Properties Red, rhomboid crystals.Soluble in pyridine and dilute sodium hydroxide; slightly soluble in water and organic solvents. Combustible.
  • Uses Experimental treatment of arteriosclerosis by increasing oxygen diffusion through arterial walls, thus decreasing buildup of cholesterol.
  • Uses Crocetin is a carotenoid derived from saffron, and is shown to have anticancer effects in both human adenocarcinoma gastric cancer cells and rat model of gastric cancer.
  • Definition ChEBI: A 20-carbon dicarboxylic acid which is a diterpenoid and natural carotenoid. Found in the crocus flower, it has been administered as an anti-fatigue dietary supplement.
  • Biological Activity Crocetin is a natural apocarotenoid dicarboxylic acid, found naturally in saffron crocus and gardenia flowers, th at has been shown to exhibit antioxidant, antiproliferative, anti-inflammatory, cardioprotective, neuroprotective, and antinociceptive activity.
  • Anticancer Research It is a natural apocarotenoid dicarboxylic acid obtained from saffron, and saffron isa spice from the flower of the Saffron crocus and present in the dry stigmas of theplant Crocus sativus which can be used as a food colorant. It is reported to be anovel anticancer agent against hepatocellular carcinoma, pancreatic cancer, lungcancer, skin carcinoma, breast cancer, and colorectal cancer. It inhibits the nucleicacid synthesis, enhances antioxidant system, induces apoptosis, hinders growthfactor signaling pathways, and thus affects the growth of cancer cells. It showseffects in the reduction of LPS-induced nitric oxide release; in the reduction ofproduced IL-1β, TNF-α, and intracellular ROS; in the activation of NF-κB; and inthe blockade of LPS (Wang et al. 2012; Gutheil et al. 2012).
  • target COX | NO
Crocetin Preparation Products And Raw materials
Raw materials
Preparation Products
Crocetin Suppliers
Global(216)Suppliers
  • Supplier：
    BINBO BIOLOGICAL CO.,LTD
  • Tel： +8618629063126
  • Email：info@binbobiological.com
  • Country：China
  • ProdList：451
  • Advantage：58
  • Supplier：
    Henan Tianfu Chemical Co.,Ltd.
  • Tel：+86-0371-55170693<br/>+86-19937530512
  • Email：info@tianfuchem.com
  • Country：China
  • ProdList：21628
  • Advantage：55
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：sales@coreychem.com
  • Country：China
  • ProdList：29859
  • Advantage：58
  • Supplier：
    BOC Sciences
  • Tel：+1-631-485-4226
  • Email：inquiry@bocsci.com
  • Country：United States
  • ProdList：19552
  • Advantage：58
Crocetin Spectrum
27876-94-4, CrocetinRelated Search:
  • Carotenoids
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  • 标准品
  • C20H24O4
  • 藏红酸(藏红花酸)
  • 藏红花酸/萜类
  • 藏花酸标准品
  • 藏红花酸|蕃紅[花]酸标准品 [干冰运输
  • 西红花酸(及钠盐)
  • 西红花酸(及其钠、钾盐)
  • (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-四甲基十六碳-2,4,6,8,10,12,14-七烯二酸
  • 蕃紅[花]酸对照品
  • 蕃紅[花]酸标准品
  • 藏红花酸(番红花酸)
  • TRANS-CROCETINE
  • 藏红花酸|蕃紅[花]酸标准品
  • 反式-藏花酸
  • 藏红花酸(反式),西红花酸
  • 藏红花酸(反式)
  • 蕃紅[花]酸
  • TRANS-藏花酸
  • 臧红花酸
  • 藏红花酸 (西红花酸)
  • 藏花酸
  • 藏红花酸(95%)
  • 西红花酸
  • 藏红花酸,藏花酸,番红花酸,西红花酸
  • 27876-94-4
  • trans-Crocetin-98%
  • 8,8'-DIAPOCAROTENEDIOIC
  • TRANS-CROCETIN
  • CROCETIN
  • Crocetin(stable)
  • Crocetin (6CI)
  • a-Crocetin
  • 8,8'-Diapo-y,y-carotenedioic acid
  • TIANFU-8,8'-DIAPOCAROTENEDIOIC ACID
  • 2,4,6,8,10,12,14-Hexadecaheptaenedioic acid, 2,6,11,15-tetramethyl-, (2E,4E,6E,8E,10E,12E,14E)-
  • trans-Crocetine
  • (2Z,4E,6Z,8E,10E,12E,14Z)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioic acid
  • Transcrocetin (Synonyms: trans-Crocetin)
  • Crocetin,trans-Crocetin

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