Uses
Analgesic (narcotic).
Definition
ChEBI: Oxymorphone hydrochloride is a member of phenanthrenes.
brand name
Numorphan (Endo); Opana (Endo).
Clinical Use
Oxymorphone is a potent μ agonist (10 times greater than morphine) that is used to treat severe
pain. It is used by intramuscular, subcutaneous, intravenous, and rectal routes of administration.
The intramuscular dose of oxymorphone (1 mg) has a half-life of 3 to 4 hours. It is a Schedule II
drug. Oxymorphone, because of its 14-hydroxy group, has low antitussive activity.
Safety Profile
Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx and HCl.
