ChemicalBook > CAS DataBase List > DMT-2'O-Methyl-rU Phosphoramidite

DMT-2'O-Methyl-rU Phosphoramidite

DMT-2'O-Methyl-rU Phosphoramidite Structure
DMT-2'O-Methyl-rU Phosphoramidite
  • CAS No.110764-79-9
  • Chemical Name:DMT-2'O-Methyl-rU Phosphoramidite
  • CBNumber:CB5500323
  • Molecular Formula:C40H49N4O9P
  • Formula Weight:760.82
  • MOL File:110764-79-9.mol
DMT-2'O-Methyl-rU Phosphoramidite Property
  • storage temp. Sealed in dry,2-8°C
  • solubility DMSO : 100 mg/mL (131.44 mM; Need ultrasonic)
  • form powder
  • pka 9.39±0.10(Predicted)
  • color white to off-white
  • biological source non-animal source (no BSE/TSE risk)
  • InChIKey UVUOJOLPNDCIHL-XKZJCBTISA-N
  • SMILES C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OC)[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C |&1:25,27,36,39,r|
  • UNSPSC Code 41116105
  • NACRES NA.51
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
DMT-2'O-Methyl-rU Phosphoramidite Price More Price(9)
  • Brand: Sigma-Aldrich(India)
  • Product number: U211180
  • Product name : DMT-2′O-Methyl-rU Phosphoramidite
  • Purity: configured for PerkinElmer, configured for Polygen
  • Packaging: 1G
  • Price: ₹8508.45
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: U211180
  • Product name : DMT-2′O-Methyl-rU Phosphoramidite
  • Purity: configured for PerkinElmer, configured for Polygen
  • Packaging: 0.5G
  • Price: ₹8952.28
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: U211150
  • Product name : DMT-2′O-Methyl-rU Phosphoramidite
  • Purity: configured for ?KTA? and OligoPilot?
  • Packaging: 2G
  • Price: ₹15956.05
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: U211150
  • Product name : DMT-2′O-Methyl-rU Phosphoramidite
  • Purity: configured for ?KTA? and OligoPilot?
  • Packaging: 5G
  • Price: ₹40582.93
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: U211150
  • Product name : DMT-2′O-Methyl-rU Phosphoramidite
  • Purity: configured for ?KTA? and OligoPilot?
  • Packaging: 10G
  • Price: ₹81122.55
  • Updated: 2022/06/14
  • Buy: Buy

DMT-2'O-Methyl-rU Phosphoramidite Chemical Properties,Usage,Production

  • Characteristics DMT-2′O-Methyl-rU Phosphoramidite belongs to the class of 2′O-Methyl RNA Phosphoramidites. Its key features include:
    High yield of crude oligonucleotides Compatible with DNA synthesis;
    Can be employed together with DNA or RNA phosphoramidites in the same synthesis to produce mixmer oligonucleotides;
    Recommended deprotection conditions are 8 hours at 55 deg C using concentrated ammonia solution, or with AMA (concentrated ammonia/40% aqueous methylamine I/I, v/v) for 10 minutes at 65 deg C;
    Purification and other downstream processing of fully modified 2′OMethyl RNA oligonucleotides are simpler than in the case of RNA, as no special precautions are required to provide protection against nucleolytic degradation;
    Synthesis of 2′O-Methyl RNA oligonucleotides is similar to standard DNA synthesis but requires an elongated coupling time (recommended is 6minutes compared to 90 seconds for DNA monomers);
    2′O-Methyl RNA phosphoramidites are also available with fast deprotection chemistry.
  • Uses DMT-2'O-Methyl-rU Phosphoramidite is a white to off-white powder and is used as a pharmaceutical intermediate for pharmaceutical synthesis and scientific research.
  • Application 2′O-Methyl RNA nucleoside including DMT-2′O-Methyl-rU Phosphoramidite can be advantageously incorporated in nucleic acid probes with RNA or DNA for in-vivo or in-vitro applications to convey nuclease resistance.The unique combination of properties of 2′O-Methyl RNA had found widespread use in the fields of:
    Diagnostic probes
    Aptamer and ribozyme development
    Mixed 2′O-Methyl-RNA/DNA antisense molecules
DMT-2'O-Methyl-rU Phosphoramidite Preparation Products And Raw materials
Raw materials
Preparation Products
DMT-2'O-Methyl-rU Phosphoramidite Suppliers
Global(182)Suppliers
  • Supplier：
    Wuhu Nuowei chemistry Co., Ltd.
  • Tel：+86-0553-2911116-802<br/>+86-18055311600
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    career henan chemical co
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    Yunbio Tech Co.,Ltd.
  • Tel：+86-010-60605551<br/>+86-18046518538
  • Email：yunbiochem@126.com
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    BOC Sciences
  • Tel：+1-631-485-4226
  • Email：inquiry@bocsci.com
  • Country：United States
  • ProdList：19552
  • Advantage：58
DMT-2'O-Methyl-rU Phosphoramidite Spectrum
110764-79-9, DMT-2'O-Methyl-rU PhosphoramiditeRelated Search:
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  • 高端化学品
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  • 有机化工
  • 化学试剂
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  • 2'-OME-U 亚磷酰胺单体/110764-79-9
  • DMT-2'-O-ME-U-CE 亚磷酰胺单体
  • 化合物 DMT-2'O-METHYL-RU PHOSPHORAMIDITE
  • 胞苷杂质15
  • (2R,3R,4R,5R)-2-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-5-(2,4-二氧代-3,4-二氢嘧啶-1(2H)-基)-4-甲氧基四氢呋喃-3-基(2-氰基乙基)二异丙基磷脒
  • 5'-O-(4, 4'-DIMETHOXYTRITYL)-2'-O-METHYL-URIDINE-3'-CE-PHOSPHORAMIDITE
  • (2R,3R,4R,5R)-2-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-5-(2,4-二氧代-3,4-二氢嘧啶-1(2H)-基)-4-甲氧基四氢呋喃-3-基(2-氰基乙基)二异丙基亚磷酰胺
  • 2'-OME-U 亚磷酰胺单体
  • DMT-2'-O-甲基-RU亚磷酰胺
  • 2'-OME-U-CE
  • 2'-OME-DU亚磷酰胺单体
  • 5'-O-(4,4-二甲氧基三苯甲基)-2'-O-甲基尿苷-3'-(2-氰基乙基-N,N-二异丙基)亚磷酰胺 6级
  • 2'-0ME-UPHOSPHORAMIDITE
  • 5'-O-DMT-2'-OME-U-CE
  • 2'-O-ME-亚磷酰胺单体2'-OME-U
  • 2'-OME-U-CE-亚磷酰胺
  • (2R,3R,4R,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-METHOXYTETRAHYDROFURAN-3-YL (2-CYANOETHYL) DIISOPROPYLPHOSPHORAMIDITE
  • 5'-O-DMT-2'-甲氧基尿苷-3'-氰乙氧基亚磷酰胺
  • 5'-O-(4,4-二甲氧基三苯甲基)-2'-O-甲基尿苷-3'-(2-氰基乙基-N,N-二异丙基)亚磷酰胺
  • 2'-甲氧基尿苷 亚磷酰胺单体
  • DMT-2′O-甲基-RU酰胺
  • 甲氧RU
  • 110764-79-9
  • Cytidine Impurity 15
  • 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • 2'-Deoxy-2'-O-Me-5'-O-DMT-Uridine-3'-CED Phosphoramidite
  • 2'-OMe-rU Phosphoramidite
  • 2'-O-Me-5'-O-DMT-U-3'-CE-Phosphoramidite
  • 2'-O-Methyl Uridine CED Phosphoramidite
  • 2'-OMe-U-CE-Phosphoramidite
  • 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-methoxy-tetrahydrofuran-3-yl]oxy-(diisopropylamino)phosphanyl]oxypropanenitrile
  • DMT-2'-O-Me-U-CE Phosphoramidite
  • DMT-2'O-Methyl-rU Phosphoramidite
  • 2'-OMe-U Phosphoramidite
  • 5'-ODMT-2'-OMe Uridine-3'-OCEPA
  • 2’-OMe -dU Amidite
  • DMTr-2'-O-Me-rU-3'-CE-Phosphoramidite
  • 2'-OMe-Uridine Amidite
  • 5'-O-DMT-2'-OMe- Uridine -3’-Cyanoethyl Phosphoramidite

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