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1-ACETYLINDOLINE

CAS No.16078-30-1
Chemical Name:1-ACETYLINDOLINE
CBNumber:CB5487514
Molecular Formula:C10H11NO
Formula Weight:161.2
MOL File:16078-30-1.mol

1-ACETYLINDOLINE Property

Melting point 102-104 °C(lit.)
Boiling point 125-130 °C(Press: 1 Torr)
Density 1.144±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 1.13±0.20(Predicted)
CAS DataBase Reference 16078-30-1(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

Safety

Safety Statements :22-24/25
WGK Germany :3
RTECS :NM1892500
HS Code :2933998090

NFPA 704:

	1
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H302-H317
Precautionary statements P280

1-ACETYLINDOLINE Price More Price(1)

Brand: Sigma-Aldrich(India)
Product number: 379492
Product name : 1-Acetylindoline
Purity: 98%
Packaging: 5G
Price: ₹4384.13
Updated: 2022/06/14
Buy: Buy

1-ACETYLINDOLINE Chemical Properties,Usage,Production

Uses 1-(2,3-Dihydroindol-1-yl)ethanone is an intermediate used for preparation of triazolothiadiazepine dioxide derivatives, halo-substituted aromatic amides and [[(phenyl)piperazinyl]alkyl]indolyl]ethanone.
Uses • ;Reactant for preparation of triazolothiadiazepine dioxide derivatives1• ;Reactant for preparation of halo-substituted aromatic amides2• ;Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists3• ;Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents4• ;Reactant for regioselective ortho Suzuki-Miyaura coupling reaction5
Uses
- Reactant for preparation of triazolothiadiazepine dioxide derivatives
- Reactant for preparation of halo-substituted aromatic amides
- Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists
- Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents
- Reactant for regioselective ortho Suzuki-Miyaura coupling reaction
Synthesis Reference(s) Tetrahedron, 52, p. 7525, 1996 DOI: 10.1016/0040-4020(96)00266-9
Tetrahedron Letters, 24, p. 561, 1983 DOI: 10.1016/S0040-4039(00)81464-1
General Description 1-Acetylindoline, a substituted indole, is a tertiary amide having bulky N-groups. Its reduction to the corresponding amine, by reaction with silane in the presence of MoO₂Cl₂ (catalyst), has been reported.