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t-Boc-N-amido-PEG1-NHS ester

t-Boc-N-amido-PEG1-NHS ester Structure
t-Boc-N-amido-PEG1-NHS ester
  • CAS No.1260092-55-4
  • Chemical Name:t-Boc-N-amido-PEG1-NHS ester
  • CBNumber:CB54849668
  • Molecular Formula:C14H22N2O7
  • Formula Weight:330.33
  • MOL File:1260092-55-4.mol
t-Boc-N-amido-PEG1-NHS ester Property
  • Density 1.26±0.1 g/cm3(Predicted)
  • pka 12.21±0.46(Predicted)
  • form Solid
  • color White to off-white
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

t-Boc-N-amido-PEG1-NHS ester Chemical Properties,Usage,Production

  • Description t-Boc-N-amido-PEG1-NHS ester is a PEG linker containing NHS ester and Boc-protected amine moieties. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
  • Uses Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • IC 50 PEGs; Alkyl/ether
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-Boc-N-amido-PEG1-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
t-Boc-N-amido-PEG1-NHS ester Suppliers
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t-Boc-N-amido-PEG1-NHS ester Spectrum
1260092-55-4, t-Boc-N-amido-PEG1-NHS esterRelated Search:
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  • 氨基叔丁酯-一聚乙二醇-NHS 酯
  • 1260092-55-4
  • Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
  • BocNH-PEG1-CH2CH2COONHS/Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
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  • Boc-N-PEG1-C2-NHS ester
  • BocNH-PEG1-CH2CH2COONHS
  • t-Boc-N-amido-PEG1-NHS ester

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