ChemicalBook > CAS DataBase List > t-Boc-Aminoxy-PEG4-alcohol
t-Boc-Aminoxy-PEG4-alcohol
- CAS No.918132-14-6
- Chemical Name:t-Boc-Aminoxy-PEG4-alcohol
- CBNumber:CB43062661
- Molecular Formula:C13H27NO7
- Formula Weight:309.36
- MOL File:918132-14-6.mol
t-Boc-Aminoxy-PEG4-alcohol Property
- Density 1.111±0.06 g/cm3(Predicted)
- pka 14.36±0.10(Predicted)
- form Viscous Liquid
- color Light yellow to yellow
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
t-Boc-Aminoxy-PEG4-alcohol Chemical Properties,Usage,Production
- Description t-Boc-Aminooxy-PEG4-alcohol is a PEGreagent with a Boc-protected aminooxy group and an alcohol group. The hydrophilic PEG spacer increases solubility in aqueous media. The protected aminooxy can be deprotected under mild acidic conditions and then can react with an aldehyde to form a stable oxime linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
- Uses Boc-Aminoxy-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
- IC 50 PEGs; Alkyl/ether
- References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-Boc-Aminoxy-PEG4-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
Global(28)Suppliers
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918132-14-6, t-Boc-Aminoxy-PEG4-alcoholRelated Search:
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- peg
- 抑制剂
- 化合物 BOC-AMINOXY-PEG4-OH
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- 918132-14-6
- t-Boc-Aminooxy-PEG4-alcohol boc
- 3,6,9,12-Tetraoxa-2-azatetradecanoic acid, 14-hydroxy-, 1,1-dimethylethyl ester
- Boc-Aminooxy-PEG4
- t-Boc-Aminooxy-PEG4-alcohol
- Reaxys ID: 11161875
- Boc-Aminoxy-PEG4-OH
- Boc-Aminooxy-PEG4-alcohol
- t-Boc-Aminoxy-PEG4-alcohol
