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DIMETHYLZINC

CAS No.544-97-8
Chemical Name:DIMETHYLZINC
CBNumber:CB5353482
Molecular Formula:C2H6Zn
Formula Weight:95.46
MOL File:544-97-8.mol

DIMETHYLZINC Property

Melting point -42°C
Boiling point 44-46 °C
Density 0.92 g/mL at 20 °C
Flash point 30 °F
storage temp. 0-6°C
form liquid
color colorless
Sensitive Air & Moisture Sensitive
Merck 14,3263
BRN 3587195
InChIKey AXAZMDOAUQTMOW-UHFFFAOYSA-N
CAS DataBase Reference 544-97-8(CAS DataBase Reference)
FDA UNII 8H6R0N8W2F
EPA Substance Registry System Zinc, dimethyl- (544-97-8)
UNSPSC Code 12352103
NACRES NA.22

Safety

Hazard Codes :F,C,N,Xn
Risk Statements :11-14-34-50/53-65-67-63-51/53-48/20-17-14/15-36/38
Safety Statements :26-45-61-62-60-43-36/37/39-33-29-16-46-43A-36/37
RIDADR :UN 3399 4.3/PG 2
WGK Germany :2
F :10-23
TSCA :Yes
HazardClass :4.2
PackingGroup :I
HS Code :29319090
Hazardous Substances Data :544-97-8(Hazardous Substances Data)

NFPA 704:

	4
3		2
	W

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H225-H250-H260-H304-H314-H336-H361d-H373-H410-H261-H252-H318-H400
Precautionary statements P210-P222-P223-P231+P232-P370+P378-P422-P261-P273-P303+P361+P353-P305+P351+P338-P405-P422a-P501a

DIMETHYLZINC Price More Price(2)

Brand: Sigma-Aldrich(India)
Product number: 417246
Product name : Dimethylzinc solution
Purity: 1.0?M in heptane
Packaging: 50ML
Price: ₹27647.05
Updated: 2022/06/14
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Brand: ALFA India
Product number: ALF-039563-14
Product name : Dimethylzinc, 96%
Purity:
Packaging: 25g
Price: ₹114126
Updated: 2022/05/26
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DIMETHYLZINC Chemical Properties,Usage,Production

Chemical Properties Clear colorless liquid
Uses Activator for radical trifluoromethylation of silyl enol ethers leading to α-trifluoromethyl ketones.1
Uses Dimethylzinc is pharmaceutical compound comprising Hemiasterlin derivatives and its antibody conjugate for treatment of cancer.
Uses Dimethylzinc solution can be used as:
- A catalyst with nickel for the stereoselective C?2 alkenylation and dialkenylation of pyridine derivatives by alkynes to give monoalkenylation products.
- A reagent with aldehydes and 2-methoxyaniline for the synthesis of enantioselective alkyl and aralkyl secondary amines via one-pot three-component coupling reaction in the presence of zirconium tetraisopropoxide.
- A methylating reagent for methylation of fluoroalkylated pyruvates in the presence of copper/chiral diphosphine catalyst.
Definition ChEBI: Dimethylzinc is a dialkylzinc compound.
General Description Mobile liquid, with peculiar garlic odor.
Air & Water Reactions Highly flammable. Ignites in air and burns with a blue flame giving off a peculiar garlicky odor. Explodes in oxygen or ozone. Reacts violently with water to generate methane [Merck, 11th ed., 1989; Brauer(1965)]. Very slow oxidation with traces of air to give methylzinc methylate.
Reactivity Profile DIMETHYLZINC is very reactive, acts as a strong reducing agent. Combines with acids, with alcohols (methanol, ethanol), and 2-2-dichloropropane as well as with water with explosive violence. When heated to decomposition emits toxic fumes of zinc oxide [Bretherick, 5th ed., 1995, p. 354]. Oxidants may yield peroxide formation, which is explosive.
Health Hazard Inhalation of mist or vapor causes immediate irritation of upper respiratory tract. Excessive or prolonged inhalation of fumes from ignition or decomposition may cause ``metal fume fever'' (sore throat, headache, fever, chills, nausea, vomiting, muscular aches, perspiration, constricting sensation in lungs, weakness, sometimes prostration). Symptoms usually last 12-24 hrs. Eyes are immediately and severely irritated by liquid, vapor, or dilute solutions. If not removed by thorough flushing with water, chemical may permanently damage cornea. Skin will undergo thermal and acid burns when chemical reacts with moisture in skin. Unless washed quickly, skin may be scarred. Treat dilute solutions with same precautions as concentrated liquid. Ingestion, while unlikely, would cause immediate burns at site of contact. Nausea, vomiting, cramps, and diarrhea may follow. Tissues may ulcerate if not treated.