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NBQX DISODIUM SALT

NBQX DISODIUM SALT Structure
NBQX DISODIUM SALT
  • CAS No.118876-58-7
  • Chemical Name:NBQX DISODIUM SALT
  • CBNumber:CB5274224
  • Molecular Formula:C12H8N4O6S
  • Formula Weight:336.28
  • MOL File:118876-58-7.mol
NBQX DISODIUM SALT Property
  • Melting point 361°C
  • Density 1.6027 (rough estimate)
  • refractive index 1.6000 (estimate)
  • storage temp. Inert atmosphere,2-8°C
  • solubility methanol: 0.25 mg/mL
  • form solid
  • pka 7.55±0.20(Predicted)
  • color yellow
  • Water Solubility H2O: >10mg/mL
  • Stability Freezer at -20°C
  • InChIKey UQNAFPHGVPVTAL-UHFFFAOYSA-N
  • FDA UNII 8LZ6Q43V2S
  • UNSPSC Code 12352200
  • NACRES NA.77
Safety
  • Hazard Codes  :Xi
  • Risk Statements  :36/37/38
  • Safety Statements  :26-36
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P264-P271-P280-P302+P352-P305+P351+P338
NBQX DISODIUM SALT Price More Price(4)
  • Brand: Sigma-Aldrich(India)
  • Product number: N183
  • Product name : NBQX disodium salt hydrate
  • Purity: ≥98% (HPLC)
  • Packaging: 5MG
  • Price: ₹28296.55
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: N183
  • Product name : NBQX disodium salt hydrate
  • Purity: ≥98% (HPLC)
  • Packaging: 25MG
  • Price: ₹123166.85
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: N171
  • Product name : NBQX hydrate
  • Purity: powder, ≥98% (HPLC)
  • Packaging: 5MG
  • Price: ₹25059.88
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: N171
  • Product name : NBQX hydrate
  • Purity: powder, ≥98% (HPLC)
  • Packaging: 25MG
  • Price: ₹112287.73
  • Updated: 2022/06/14
  • Buy: Buy

NBQX DISODIUM SALT Chemical Properties,Usage,Production

  • Chemical Properties Yellow Crystalline Solid
  • Uses A potent and discriminating antagonist for AMPA binding sites. This compound has neuroprotective properties.
  • Uses NBQX disodium salt hydrate has been used:
    • in N-methyl-D-aspartate receptor (NMDAR) kinetic studies
    • as an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist for the electrophysiological studies cultured neurons
    • in the extracellular solution for current/voltage (I/V) relationship and rectification index experiments in excitatory postsynaptic currents (EPSCs) mediated by NMDA receptors (EPSCNMDAR)

  • Definition ChEBI: 2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline is a member of naphthalenes and a sulfonic acid derivative.
  • General Description NBQX [2,3-dihydroxy-6-nitro-7-sulphamoyl-benzo(F)quinoxaline] is a competitive antagonist, which shows high affinity to 2-amino-3-hydroxy-5-methyl-4-isoxazol propionic acid (AMPA) receptor than kainite receptor.
  • Biological Activity Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo . More water soluble disodium salt of NBQX (2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide ). Also available as part of the AMPA Receptor Tocriset™ .
  • Biochem/physiol Actions NBQX [2,3-dihydroxy-6-nitro-7-sulphamoyl-benzo(F)quinoxaline], an anticonvulsant provides protection against white matter damage in spinal cord crush injury and also protects oligodendrocyte in experimental autoimmune encephalomyelitis (EAE). However, its role in preventing inflammation in EAE is not yet clear.
  • storage Room temperature
NBQX DISODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
NBQX DISODIUM SALT Suppliers
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NBQX DISODIUM SALT Spectrum
118876-58-7, NBQX DISODIUM SALTRelated Search:
  • Neurochemicals
  • Heterocyclic Compounds
  • Glutamate receptor
  • Glutamate
  • 合成有机化合物配体
  • 原料药
  • 抑制剂
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Ion Channels
  • Ionotropic Glutamate Receptor Modulators
  • Ligand-Gated Ion Channels
  • C12H6N4O6SNa2
  • C12H8N4O6S
  • C12H6N4Na2O6S
  • 二羟基喹酮,10 MM DMSO 溶液
  • NBQX DISODIUM SALT (MM/ML),AMPA / KAINATE拮抗剂
  • NBQX,AMPA / KAINATE拮抗剂
  • NBQX,AMPA /海藻酸盐拮抗剂
  • NBQXHYDRATEPOWDER,>=98%(HPLC)
  • 6-硝基-2,3-二氧代-1,2,3,4-四氢苯并[F]喹喔啉-7-磺酰胺
  • 1,2,3,4-四氢-6-硝基-2,3-二氧代苯并[F]喹喔啉-7-磺酰胺
  • 二羟基喹酮
  • 6 -硝基- 7 - 硫氨基苯并[F]喹喔啉-2,3二酮
  • 1,2,3,4-四氢-6-硝基-2,3-二氧苯并[F]喹喔啉-7-磺钠盐水合物
  • 118876-58-7
  • NBQX (FG9202)
  • NBQX, 10 mM in DMSO
  • NBQX, AMPA / kainate antagonist
  • NBQX disodium salt (mM/ml), AMPA / kainate antagonist
  • Dihydroxyquinone
  • 6-Nitro-2,3-dioxo-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide
  • Benzo[f]quinoxaline-7-sulfonamide, 1,2,3,4-tetrahydro-6-nitro-2,3-dioxo-
  • NBQX NEW
  • FG9202;FG-9202;FG 9202
  • disodium 6-nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-diolate hydrate
  • 1,2,3,4-tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide disodium salt
  • NBQX HYDRATE
  • NBQX DISODIUM (FG 9202) NEUROPROTECTIVE GLUTA
  • FG 9202 DISODIUM
  • FG 9202
  • 2,3-DIOXO-6-NITRO-1,2,3,4-TETRAHYDROBENZO[F]QUINOXALINE-7-SULFONAMIDE DISODIUM SALT
  • 2,3-DIOXO-6-NITRO-1,2,3,4-TETRAHYDROBENZO[F]QUINOXALINE-7-SULFONAMIDE
  • 2,3-DIHYDROXY-6-NITRO-7-SULPHAMOYLBENZO(F)-QUINOXALINE 2NA
  • 2,3-DIHYDROXY-6-NITRO-7-SULPHAMOYLBENZO(F)-QUINOXALINE
  • 1,2,3,4-TETRAHYDRO-6-NITRO-2,3-DIOXO-BENZO[F]QUINOXALINE-7-SULFONAMIDE DISODIUM
  • 1,2,3,4-TETRAHYDRO-6-NITRO-2,3-DIOXO-BENZO[F]QUINOXALINE-7-SULFONAMIDE
  • 6-NITRO-7-SULPHAMOYLBENZO(F)-QUINOXALINE-2,3-DIONE 2NA
  • 6-NITRO-7-SULPHAMOYLBENZO(F)-QUINOXALINE-2,3-DIONE
  • 6-NITRO-7-SULFAMOYLBENZO[F]QUINOXALINE-2,3-DIONE, DISODIUM SALT
  • 6-NITRO-7-SULFAMOYLBENZO[F]QUINOXALINE-2,3-DIONE
  • 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline
  • 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide hydrate
  • NBQX DISODIUM SALT
  • NBQX DISODIUM
  • 6-Nitro-2,3-dioxo-2,3-dihydrobenzo[f]quinoxaline-7-sulfonamide
  • NBQX disodium salt hydrate

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