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(+/-)-THIOPENTAL

(+/-)-THIOPENTAL Structure
(+/-)-THIOPENTAL
  • CAS No.76-75-5
  • Chemical Name:(+/-)-THIOPENTAL
  • CBNumber:CB5265910
  • Molecular Formula:C11H18N2O2S
  • Formula Weight:242.34
  • MOL File:76-75-5.mol
(+/-)-THIOPENTAL Property
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302
  • Precautionary statements P301+P312+P330

(+/-)-THIOPENTAL Chemical Properties,Usage,Production

  • Chemical Properties Off-White Solid
  • Originator Pentothal,Abbott
  • Uses A thio-derivative of Barbituric acid. Controlled substance (depressant). Anesthetic
  • Definition ChEBI: Thiopental is a barbiturate, the structure of which is that of 2-thiobarbituric acid substituted at C-5 by ethyl and sec-pentyl groups. It has a role as an anticonvulsant, a sedative, an environmental contaminant, a xenobiotic, a drug allergen and an intravenous anaesthetic. It is functionally related to a 2-thiobarbituric acid. It is a conjugate acid of a thiopental(1-).
  • Manufacturing Process 130 g of ethyl (1-methylbutyl) malonic ester is added to a concentrated solution of sodium ethylate prepared from 34 g of sodium in absolute alcohol; with stirring, 60 g of finely divided thiourea is added, and, the mixture refluxed for 10 hours. Most or all of the solvent is evaporated and the residual mass is dissolved in cold water. The barbituric acid derivative so formed is precipitated by the addition of dilute hydrochloric acid. It may be 1 purified by solution in dilute ammonium hydroxide solution and precipitated by carbon dioxide, followed by recrystallization from 95% alcohol. The ethyl (1- methylbutyl)thiobarbituric acid so obtained is a white crystalline solid, melting at 158-159°C and readily forming salts with alkalies.
  • brand name Thiopental is BAN.
  • Therapeutic Function Narcotic analgesic, Anesthetic
  • Safety Profile Poison by intraperitoneal, intravenous, and rectal routes. Moderately toxic by ingestion. An experimental teratogen. Human mutation data reported. A short-acting intravenous anesthetic. When heated to decomposition it emits very toxic fumes of NOx and SOx
(+/-)-THIOPENTAL Preparation Products And Raw materials
Raw materials
Preparation Products
(+/-)-THIOPENTAL Suppliers
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(+/-)-THIOPENTAL Spectrum
76-75-5, (+/-)-THIOPENTALRelated Search:
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • 对照品
  • Analytical Standards
  • TF - TO
  • Analytical Chromatography Product Catalog
  • Alphabetic
  • C11H18N2O2S
  • 硫喷妥塔尔
  • 硫喷妥钠(巴比妥杂质10)
  • 硫喷妥钠系统适应性 EP标准品
  • 硫喷妥羧酸
  • 戊硫代巴比妥
  • (±)戊硫代巴比妥 溶液
  • 76-75-5
  • Thiopental for system suitability (Y0001478)
  • ('+/-)-THIOPENTAL
  • Thiopental for system suitability CRS
  • Thiopental CRS
  • 5-ethyl-5-pentan-2-yl-2-sulfanylidene-1,3-diazinane-4,6-dione
  • 5-Ethyl-5-(1-methylbutyl)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
  • 5-ethyl-5-(1-methylbutyl)-2-thio-barbituricaci
  • 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-
  • (1h,5h)-pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-6
  • THIOPENTAL
  • (+/-)-THIOPENTAL
  • THIOPENTONE
  • Tiopentale
  • Thiothal
  • Thiopentobarbituric acid
  • Thiopentobarbitone
  • Thiopentobarbital
  • Thiomebumal
  • Pentothiobarbital
  • Pentothal
  • Penthiobarbital
  • Nesdonal
  • Intraval
  • Barbituric acid, 5-ethyl-5-(1-methylbutyl)-2-thio-
  • Thiopental for system suitability
  • Thiopental CIII (250 mg)
  • 5-Ethyl-5-[(S)-1-methylbutyl]-2-thioxo-1,2-dihydropyrimidine-4,6(3H,5H)-dione
  • (+,-)-thiopental free acid--dea*schedule iii item
  • (+-)-thiopental methanol solution
  • 5-Ethyl-5-(1-methylbutyl)-2-thiobarbitirobic acid
  • PENTOTHAL ACID
  • Barbituric acid, 5-ethyl-5-(1-methylbutyl)-2-thio- (8CI)
  • 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo- (9CI)
  • 2-Thio-5-ethyl-5-sec-pentylbarbituric acid
  • (±)thiopental solution
  • 5-Ethyldihydro-5-(1-methylbutyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione
  • 5-ETHYL-5-PENTAN-2-YL-2-SULFANYL-1H-PYRIMIDINE-4,6-DIONE
  • 5-ETHYL-5-[1-METHYLBUTYL]-2-THIOBARBITURIC ACID

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