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γ-Linolenic Acid Ethyl Ester

γ-Linolenic Acid Ethyl Ester Structure
γ-Linolenic Acid Ethyl Ester
  • CAS No.31450-14-3
  • Chemical Name:γ-Linolenic Acid Ethyl Ester
  • CBNumber:CB5229451
  • Molecular Formula:C20H34O2
  • Formula Weight:306.48
  • MOL File:31450-14-3.mol
γ-Linolenic Acid Ethyl Ester Property
  • Boiling point 390.6±31.0 °C(Predicted)
  • Density 0.893±0.06 g/cm3(Predicted)
  • storage temp. −20°C
  • solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
  • form liquid
  • color Colourless
  • Stability Light Sensitive
  • InChI InChI=1S/C20H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22-4-2/h8-9,11-12,14-15H,3-7,10,13,16-19H2,1-2H3/b9-8-,12-11-,15-14-
  • InChIKey MJLYTDAIYLGSRZ-ORZIMQNZSA-N
  • SMILES C(OCC)(=O)CCCC/C=C\C/C=C\C/C=C\CCCCC
  • LogP 7.562 (est)
  • FDA UNII Z2942E0NCT
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H225-H319
  • Precautionary statements P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501

γ-Linolenic Acid Ethyl Ester Chemical Properties,Usage,Production

  • Description γ-Linolenic acid (GLA) is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak leukotriene B4 (LTB4) receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki value of 1 μM. GLA produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction. GLA ethyl ester is an esterified version of the free acid which is less water soluble but more amenable for the formulation of GLA-containing diets.
  • Uses γ-Linolenic Acid Ethyl Ester is used in biological studies for neoplasm inhibition of cultured carcinoma cells of human breast. This analog is also used in the evaluation of hypocholesterolemic activity in rats by comparing it with γ-Linolenic Acid (L467660).
  • Definition ChEBI: Gamma-Linolenic acid ethyl ester is a long-chain fatty acid ethyl ester.
  • Purification Methods To highly purify γ-linolenic acid (GLA) from microbial lipids, various types of zeolites were investigated in a fixed-bed column system, where a two-step desoprtion operation mode was found to be superior in selective separation of GLA. By this system, GLA ethyl ester of 98 mol% purity was obtained from a mixture of various polysaturated and unsaturated fatty acid esters using cesium Y and methyl-, dimethyl- and ethylammonium Y zeolites[1].
  • References [1] MAKOTO ARAI Hisashi M Hideki Fukuda. Selective separation of γ-linolenic acid ethyl ester using y-zeolite[J]. Journal of Fermentation Technology, 1987. DOI:10.1016/0385-6380(87)90118-X.
γ-Linolenic Acid Ethyl Ester Preparation Products And Raw materials
Raw materials
Preparation Products
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γ-Linolenic Acid Ethyl Ester Spectrum
31450-14-3, γ-Linolenic Acid Ethyl EsterRelated Search:
  • 抑制剂
  • 对照品
  • Unsaturated fatty acids and derivatives
  • Lipids
  • Esters
  • Ethyl Ester
  • Fatty Acids
  • BioChemical
  • Biochemicals and Reagents
  • Γ-亚麻酸乙酯 标准品
  • 化合物 Γ-LINOLENIC ACID ETHYL ESTER
  • 6顺,9顺,12顺-十八碳三烯酸乙酯
  • (6Z,9Z,12Z)-十八烷-6,9,12-三烯酸乙酯
  • R-亚麻酸乙酯
  • (6Z,9Z,12Z)-十八碳-6,9,12-三烯酸乙酯
  • GAMMA-亚麻酸乙酯
  • GAMMA-亚麻酸乙酯 1G
  • (6Z,9Z,12Z)-6,9,12-十八碳三烯酸乙酯
  • γ-亚麻酸乙酯
  • 31450-14-3
  • All Cis 6-9-12 Octadecatrienoic Ethyl Ester
  • Ethyl (6Z,9Z,12Z)-6,9,12- octadecatrienoic acid
  • Ethyl 6(Z),9(Z),12(Z)-octadecatrienoate
  • (6Z,9Z,12Z)-ethyl octadeca-6,9,12-trienoate
  • Ethyl Gamma-Linolenic Acid(C18:3)
  • cis-6,cis-9,cis-12 Octadecadienoic acid ethyl ester
  • Ethyl linolenate gamma@10 mg/mL in Hexane
  • Gamma Linolenic acid ethyl ester (GLA-EE)
  • Gamma Linolenic Acid Ethyl Ester (90%)
  • Ethyl (6Z,9Z,12Z)-octadeca-6,9,12-trienoate
  • Ethyl gamma-linolenic acid
  • Ethyl gamma-linolenate
  • (6Z,9Z,12Z)-6,9,12-Octadecatrienoic acid ethyl ester
  • Ethyl linolenate gamma
  • γ-Linolenic acid ethyl ester, 6,9,12-Octadecatrienoic acid ethyl ester
  • 6,9,12-Octadecatrienoic acid, ethyl ester, (6Z,9Z,12Z)-
  • DELTA 6 CIS 9 CIS 12 CIS OCTADECATRIENOIC ACID ETHYL ESTER
  • GAMMA-LINOLENIC ACID ETHYL ESTER
  • 6,9,12-OCTADECATRIENOIC ACID ETHYL ESTER

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