ChemicalBook > CAS DataBase List > 2,2'-Dithiodipyridine

2,2'-Dithiodipyridine

2,2'-Dithiodipyridine Structure
2,2'-Dithiodipyridine
  • CAS No.2127-03-9
  • Chemical Name:2,2'-Dithiodipyridine
  • CBNumber:CB5200205
  • Molecular Formula:C10H8N2S2
  • Formula Weight:220.31
  • MOL File:2127-03-9.mol
2,2'-Dithiodipyridine Property
  • Melting point 56-58 °C(lit.)
  • Boiling point 356.1±17.0 °C(Predicted)
  • Density 1.3078 (rough estimate)
  • refractive index 1.5500 (estimate)
  • Flash point 210 °C
  • storage temp. 2-8°C
  • solubility methanol: soluble50mg/mL, clear to very slightly hazy, colorless to faintly brownish-yellow
  • pka 1.52±0.19(Predicted)
  • form powder
  • color Clear colorless to yellow to tan
  • Water Solubility 5 g/L (20 ºC)
  • BRN 154629
  • InChIKey HAXFWIACAGNFHA-UHFFFAOYSA-N
  • LogP 2.530 (est)
  • CAS DataBase Reference 2127-03-9(CAS DataBase Reference)
  • FDA UNII L6X912UPBU
  • NIST Chemistry Reference Pyridine, 2,2'-dithiobis-(2127-03-9)
  • EPA Substance Registry System Pyridine, 2,2'-dithiobis- (2127-03-9)
  • UNSPSC Code 12352113
  • NACRES NA.26
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P264-P271-P280-P302+P352-P305+P351+P338
2,2'-Dithiodipyridine Price More Price(16)
  • Brand: Sigma-Aldrich(India)
  • Product number: D5767
  • Product name : 2,2′-Dithiodipyridine
  • Purity: powder
  • Packaging: 1G
  • Price: ₹2522.23
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D5767
  • Product name : 2,2′-Dithiodipyridine
  • Purity: powder
  • Packaging: 5G
  • Price: ₹6484.18
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D5767
  • Product name : 2,2′-Dithiodipyridine
  • Purity: powder
  • Packaging: 25G
  • Price: ₹24616.05
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 8.41109
  • Product name : 2,2′-Dipyridyl disulfide
  • Purity: for synthesis
  • Packaging: 5G
  • Price: ₹9510
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 143049
  • Product name : Aldrithiol™-2
  • Purity: 98%
  • Packaging: 1G
  • Price: ₹1634.58
  • Updated: 2022/06/14
  • Buy: Buy

2,2'-Dithiodipyridine Chemical Properties,Usage,Production

  • Chemical Properties white to yellowish crystalline powder
  • Uses 2,2'-Dipyridyl disulfide is a useful reagent for determination of sulfhydryl groups, preparation of amino acid active esters and the thio esters of phosphoric acid. It acts as a peptide coupling reagent and as an oxidizing agent. It is also used for the activation of glycosides.
  • Uses 2,2'-Dipyridyldisulfide, sometimes known as DPS, is used for preparing thiols and activating or protecting carboxylic acid with triphenylphosphine.
  • Uses 2,2'-Dithiodipyridine was used in the synthesis of adenosine-5′-phosphoimidazolide. It was employed with PPh3 as a condensing agent in the amidation of carboxylic acid enantiomers for HPLC separation.
  • Definition ChEBI: Aldrithiol is a member of the class of pyridines that is pyridine which is substituted by a pyridin-2-yldisulfanediyl group at position 2. It is a reagent used in molecular biology as an oxidizing agent. Also used in peptide synthesis and for detecting thiols. It has a role as an oxidising agent. It is an organic disulfide and a member of pyridines.
  • General Description 2,2'-Dithiodipyridine is a nucleocapsid zinc finger targeting compound and can abrogate the infectivity of human immunodeficiency virus type-1 virions. It is a thiol reagent.
  • Biochem/physiol Actions 2,2′-Dithiodipyridine mediates inter-unit disulfide cross-linking. It interacts with carbon nucleophiles to yield thiopyridyl derivatives.
  • Purification Methods Recrystallise the disulfide H2O from *C6H6/pet ether (6:7), ligroin or *C6H6. The picrate has m 119o (from EtOH). [Walter et al. Justus Liebigs Ann Chem 695 7785 1966, Marckwald et al. Chem Ber 33 1556 1900, Brocklehurst & Little Biochem J 133 67,78 1973, Beilstein 21 III/IV 48.] It has been used as a 1mM solution in EtOH for the spectrophotometric estimation of thiols. Essentially the thiol displaces half the disulfide molecule liberating the 2-mercaptopyridine anion, thereby shifting the from 340nm (of the disulfide) to 268nm (of the anion) at pH 9, or 278nm in H2O. (Compare
2,2'-Dithiodipyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2,2'-Dithiodipyridine Suppliers
Global(355)Suppliers
  • Supplier：
    Chongqing Chemdad Co., Ltd
  • Tel：+86-023-6139-8061<br/>+86-86-13650506873
  • Email：sales@chemdad.com
  • Country：China
  • ProdList：39894
  • Advantage：58
  • Supplier：
    Moxin Chemicals
  • Tel： +8617320513646
  • Email：mike@molcoo.com
  • Country：China
  • ProdList：9734
  • Advantage：58
  • Supplier：
    Capot Chemical Co.,Ltd.
  • Tel：+86-（0）57185586718<br/>+86-13336195806
  • Email：sales@capot.com
  • Country：China
  • ProdList：29730
  • Advantage：60
  • Supplier：
    Henan Tianfu Chemical Co.,Ltd.
  • Tel：+86-0371-55170693<br/>+86-19937530512
  • Email：info@tianfuchem.com
  • Country：China
  • ProdList：21629
  • Advantage：55
  • Supplier：
    Zjartschem
  • Tel：+86-571 87238903
  • Email：jocelynpan@zjarts.com
  • Country：CHINA
  • ProdList：988
  • Advantage：58
2,2'-Dithiodipyridine Spectrum
2127-03-9, 2,2'-Dithiodipyridine Related Search:
  • 2127-03-9
  • Coupling Reactions (Peptide Synthesis)
  • Condensation & Active Esterification
  • Biochemistry
  • Synthetic Organic Chemistry
  • Peptide Synthesis
  • Sulfur & Selenium Compounds
  • Miscellaneous Reagents
  • Heterocycles
  • Aromatics
  • 杂质对照品
  • 抑制剂
  • 高端化学
  • 中间体-有机中间体
  • 大化工产品
  • 化学试剂-精细化工
  • 化学试剂
  • 精细化工品
  • 化工中间体
  • 化工原料
  • 有机中间体
  • 生化试剂
  • 合成材料中间体
  • 原料药
  • 氨基酸及其衍生物
  • 其他生化试剂
  • 通用试剂
  • 中间体 Intermediate
  • 医药中间体
  • 中间体
  • 杂环砌块
  • 吡啶
  • 氮杂环类
  • Condensation & Active Esterification
  • Coupling Reactions (Peptide Synthesis)
  • Peptide Synthesis
  • C9 to C46
  • Amino Acid Analysis
  • BioChemical
  • Amino Acid Analysis Reagents
  • Amino Acids and Peptides
  • Biochemicals and Reagents
  • Building Blocks
  • Peptide Analysis and Characterization
  • Pyridines
  • Heterocyclic Building Blocks
  • C10H8N2S2
  • 82979
  • 2127-3-9
  • 2127-03-09
  • 21270-03-9
  • -二硫二吡啶
  • 2,2'-二硫吡啶
  • 2,2'-DIPYRIDYL DISULFIDE|||OPSS|||2,2'-二硫二吡啶|||ALDRITHIOL 2|||ORTHOPYRIDYL DISULFIDE
  • 2,2''-二硫二吡啶
  • 2,2"-二硫二二吡啶
  • 2,2'-联吡啶二硫醚
  • 2,2'-二硫二吡啶, 用于合成

Home

My