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(S)-(-)-PROPRANOLOL HYDROCHLORIDE

(S)-(-)-PROPRANOLOL HYDROCHLORIDE Structure
(S)-(-)-PROPRANOLOL HYDROCHLORIDE
  • CAS No.4199-10-4
  • Chemical Name:(S)-(-)-PROPRANOLOL HYDROCHLORIDE
  • CBNumber:CB4455695
  • Molecular Formula:C16H22ClNO2
  • Formula Weight:295.8
  • MOL File:4199-10-4.mol
(S)-(-)-PROPRANOLOL HYDROCHLORIDE Property
  • Melting point 193-195 °C(lit.)
  • storage temp. 2-8°C
  • solubility ethanol: 10 mg/mL
  • form powder
  • color White to off-white
  • optical activity [α]25/D 25.5°, c = 1.0 in ethanol(lit.)
  • Water Solubility Soluble to 100 mM in water
  • BRN 3574966
  • InChIKey ZMRUPTIKESYGQW-UQKRIMTDSA-N
  • CAS DataBase Reference 4199-10-4(CAS DataBase Reference)
  • FDA UNII YP6GDU0L78
  • UNSPSC Code 12352200
  • NACRES NA.77
Safety
  • Hazard Codes  :Xn
  • Risk Statements  :20/21/22
  • Safety Statements  :36
  • WGK Germany  :3
  • NFPA 704:
    0
    3 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302+H312+H332
  • Precautionary statements P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
(S)-(-)-PROPRANOLOL HYDROCHLORIDE Price More Price(2)
  • Brand: Sigma-Aldrich(India)
  • Product number: P8688
  • Product name : (S)-(−)-Propranolol hydrochloride
  • Purity: ≥98% (TLC), powder
  • Packaging: 100MG
  • Price: ₹12946.7
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: P8688
  • Product name : (S)-(−)-Propranolol hydrochloride
  • Purity: ≥98% (TLC), powder
  • Packaging: 500MG
  • Price: ₹43451.55
  • Updated: 2022/06/14
  • Buy: Buy

(S)-(-)-PROPRANOLOL HYDROCHLORIDE Chemical Properties,Usage,Production

  • Description (S)-(-)-Propranolol is the active enantiomer of propranolol, a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. It is also a non-specific serotonin receptor antagonist. Propanolol was one of the first β-adrenergic receptor blockers to be widely used in clinical practice for the treatment of hypertension, angina pectoris, and cardiac ischemia.
  • Chemical Properties (S)-(-)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride
  • Uses Antihypertensor;Beta-adrenergic blocking agent
  • Uses active enantiomer, 5-HT1 receptor antagonist
  • Uses The S-enantiomer of Propranolol (P831800). β?Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).
  • Biological Activity More active enantiomer of the β -adrenoceptor antagonist propranolol ((RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride ).
  • Biochem/physiol Actions (S)-(?)-Propranolol hydrochloride is biologically active enantiomer. It acts as β1 receptor antagonist in thalamocortical neurons. (S)-(?)-Propranolol hydrochloride elicits its inhibitory function on the β1 adrenoceptor in trigeminovascular pain pathway and serves as a preventive medicine in migraine.
  • storage Store at RT
  • Purification Methods The (+)-salt is the active isomer which blocks isoprenaline tachycardia and is a -adrenergic blocker. [Leclerc et al. Trends Pharmacol Sci 2 18 1981, Howe & Shanks Nature 210 1336 1966.]
(S)-(-)-PROPRANOLOL HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
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(S)-(-)-PROPRANOLOL HYDROCHLORIDE Spectrum
4199-10-4, (S)-(-)-PROPRANOLOL HYDROCHLORIDERelated Search:
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  • Asymmetric Synthesis
  • C16H22ClNO2
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  • 4199-10-4
  • (<i>S</i>)-(?)-Propranolol hydrochloride
  • (S)-Propranolol hydrochloride, beta adrenoceptor antagonist
  • Levopropranolol hydrochloride
  • (S)()Propranolol hydrochloride,(S) ( ) Propranolol hydrochloride
  • 2-Propanol, 1-(1-methylethyl)amino-3-(1-naphthalenyloxy)-, hydrochloride, (2S)-
  • (S)-[2-hydroxy-3-(naphthyloxy)propyl]isopropylammonium chloride
  • 2S-(-)-PROPANOLOL HYDROCHLORIDE
  • (S)-PROPRANOLOL HYDROCHLORIDE
  • (S)-(-)-PROPRANOLOL HYDROCHLORIDE
  • S(-)-PROPRANOLOL HCL
  • S-(-)-PROPANOLOL HCL
  • (S)-1-ISOPROPYLAMINO-3-(1-NAPHTHYLOXY)-2-PROPANOL HYDROCHLORIDE
  • (S)-(-)-1-[(1-METHYLETHYL)AMINO]-3-(1-NAPHTHALENYLOXY)-2-PROPANOL HYDROCHLORIDE
  • (2S)-(-)-Propanolol Hydrochloride≥ 95% (NMR)
  • (S)-()-Propranolol hydrochloride,(S)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride
  • (2S)-1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol hydrochloride
  • (2S)-1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol hydrochloride
  • (2S)-1-(1-Naphtyloxy)-3-(isopropylamino)-2-propanol·hydrochloric acid
  • (S)-(-)-1-(1-Methylethylamino)-3-naphthalen-1-yloxy-propan-2-ol hydrochloride
  • (S)-1-(isopropylamino)-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride
  • S-PROPANOLOL
  • S-(-)-1-Isopropylamino-3-(1-naphthoxy)-2-propanol hydrochloride
  • l-Propranolol hydrochloride
  • l-Propranolol chlorhydrate
  • L-(-)-Propranolol hydrochloride
  • 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (S)-
  • 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (2S)- (9CI)

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