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REVEROMYCIN A

REVEROMYCIN A Structure
REVEROMYCIN A
  • CAS No.134615-37-5
  • Chemical Name:REVEROMYCIN A
  • CBNumber:CB4443481
  • Molecular Formula:C36H52O11
  • Formula Weight:660.79
  • MOL File:134615-37-5.mol
REVEROMYCIN A Property
  • Boiling point 849.0±65.0 °C(Predicted)
  • Density 1.21±0.1 g/cm3(Predicted)
  • storage temp. −20°C
  • solubility DMF: soluble
  • form solid
  • pka 4.36±0.17(Predicted)
  • color tan
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
REVEROMYCIN A Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: R0654
  • Product name : Reveromycin A
  • Purity: solid
  • Packaging: 100μG
  • Price: ₹30558.98
  • Updated: 2022/06/14
  • Buy: Buy

REVEROMYCIN A Chemical Properties,Usage,Production

  • Uses Reveromycin A is a spiroketal antibiotic inhibitor of EGF mitogenic activity. Inhibits the signal transduction of the epidermal growth factor. May be used
  • Uses Reveromycin A, the dominant analogue of a complex of spiroketals isolated from a Streptomyces sp., is an inhibitor of the mitogenic activity of EGF. Reveromycin A is a G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase. Reveromycin A displays antiproliferative behaviour against human cell lines KB and K562, as well as potent antifungal activity. More recently it has been shown to induce apoptosis in osteoclasts thus inhibiting bone resorption.
  • in vivo

    Reveromycin A (20 mg/kg; twice daily; i.v.; for 3 days) significantly decreases numbers of OCs without affecting numbers of osteoblasts in normal 4-week-old male Sprague-Dawley rats[2].

REVEROMYCIN A Preparation Products And Raw materials
Raw materials
Preparation Products
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REVEROMYCIN A Spectrum
134615-37-5, REVEROMYCIN ARelated Search:
  • Antineoplastic and Immunosuppressive AntibioticsReceptor Tyrosine Kinase Biology
  • Spectrum of Activity
  • Receptor Tyrosine Kinase Inhibitors
  • Mechanism of Action
  • AntifungalAntibiotics
  • Antibiotics N-SAntibiotics
  • Antibiotics by Application
  • Antibiotics A to
  • Antibiotics
  • Interferes with Protein Synthesis
  • Epidermal Growth Factor Receptor (EGFR)Antibiotics
  • 抑制剂
  • 微生物代谢物
  • Antibiotics N-S
  • Antibiotics A to Z
  • Antibiotics
  • BioChemical
  • C36H52O11
  • 雷弗霉素A REVEROMYCIN A
  • 雷弗霉素 A
  • 134615-37-5
  • Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
  • ZESGNAJSBDILTB-OXVOKJAASA-N
  • REVEROMYCIN A

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