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DANSYLCADAVERINE

DANSYLCADAVERINE Structure
DANSYLCADAVERINE
  • CAS No.10121-91-2
  • Chemical Name:DANSYLCADAVERINE
  • CBNumber:CB4266400
  • Molecular Formula:C17H25N3O2S
  • Formula Weight:335.46
  • MOL File:10121-91-2.mol
DANSYLCADAVERINE Property
  • Melting point 137-140 °C
  • Boiling point 505.5±60.0 °C(Predicted)
  • Density 1.190±0.06 g/cm3(Predicted)
  • storage temp. −20°C
  • pka 11.96±0.50(Predicted)
  • form powder
  • color Yellow to yellowish green
  • λmax 335 nm
  • BRN 2951070
  • Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20°C for up to 1 month.
  • Biological Applications Measuring cardiac autophagic flux; treating cataract,fibrosis,Parkinson’s disease,peritoneal ovarian tumor dissemination,respiratory diseases,lung diseases,Huntington’s disease,spinobulbar atrophy,spinocerebellar ataxia,denta
  • FDA UNII I9N81SC5HD
  • UNSPSC Code 12352108
  • NACRES NA.32
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P264-P271-P280-P302+P352-P305+P351+P338
DANSYLCADAVERINE Price More Price(6)
  • Brand: Sigma-Aldrich(India)
  • Product number: D4008
  • Product name : Dansylcadaverine
  • Purity: ≥97% (TLC)
  • Packaging: 100MG
  • Price: ₹4306.8
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D4008
  • Product name : Dansylcadaverine
  • Purity: ≥97% (TLC)
  • Packaging: 250MG
  • Price: ₹8191.8
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D4008
  • Product name : Dansylcadaverine
  • Purity: ≥97% (TLC)
  • Packaging: 1G
  • Price: ₹22233.3
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 30432
  • Product name : Dansylcadaverine
  • Purity: suitable for fluorescence, BioReagent, ≥99.0% (HPLC)
  • Packaging: 100MG
  • Price: ₹6349.2
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 30432
  • Product name : Dansylcadaverine
  • Purity: suitable for fluorescence, BioReagent, ≥99.0% (HPLC)
  • Packaging: 1G
  • Price: ₹35753.1
  • Updated: 2022/06/14
  • Buy: Buy

DANSYLCADAVERINE Chemical Properties,Usage,Production

  • Description Monodansylcadaverine (MDC) is a fluorescent marker for autophagic vacuoles. It is an autofluorescent substance incorporated into multilamellar bodies by both an ion trapping mechanism and interaction with membrane lipids, exhibiting a Stokes shift and increased relative fluorescence in hydrophobic environments. MDC selectively accumulates in PaTu 8902 subcellular fractions containing the lysosomal enzymes acid phosphatase and cathepsin D, but not those containing the rough and smooth endoplasmic reticulum markers TRAM and cytochrome P450, respectively.
  • Uses Lysosomotropic fluorescent Probe
  • Uses Fluorescent substrate for the assay of transamidating enzymes.
  • Uses Dansylcadaverine is a fluorescent amine probe, which is believed to directly inhibit vesicular transport. Studies indicate that Dansylcadaverine can act as a marker used to study autophagy in the cytoplasm and vacuoles of plants and mammalian cells.
  • Definition ChEBI: Monodansylcadaverine is a sulfonamide obtained by formal condensation of the sulfo group of 5-(dimethylamino)naphthalene-1-sulfonic acid with one of the amino groups of cadaverine. It has a role as a fluorochrome, a protective agent and an EC 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitor. It is a sulfonamide, an aminonaphthalene, a tertiary amino compound and a primary amino compound. It is functionally related to a cadaverine.
  • References 1) Munafo and Colombo (2001),?A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation; Int. J. Cell Sci.,?114?3619 2) Jiang?et al. (2012),?Targeting androgen receptor leads to suppression of prostate cancer via induction of autophagy; J. Urol.,?188?1361 3) Haigler?et al.?(1980),?Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells; J. Biol. Chem., 255 1239 4) Murthy?et al. (1994),?Residue Gln-30 of human erythrocyte anion transporter is a prime site for reaction with intrinsic transglutaminase; J. Biol. Chem.,?269?22907
DANSYLCADAVERINE Preparation Products And Raw materials
Raw materials
Preparation Products
DANSYLCADAVERINE Suppliers
Global(117)Suppliers
  • Supplier：
    career henan chemical co
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  • Supplier：
    Aladdin Scientific
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  • Email：tp@aladdinsci.com
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DANSYLCADAVERINE Spectrum
10121-91-2, DANSYLCADAVERINERelated Search:
  • Naphthalene
  • 抑制剂
  • 生化试剂
  • 染料
  • 荧光探针，标记，颗粒和染色
  • Alphabetical
  • Detection
  • Fluorescent Enzyme Substrates
  • Fluorescent Probes, Labels, Particles and Stains
  • BioChemical
  • Biochemicals and Reagents
  • C17H25N3O2S
  • C17H25BN3O2S
  • 丹酰尸胺,10 MM DMSO 溶液
  • 丹磺胺
  • 单丹磺酰戊二胺
  • N-(5-氨基戊基)-5-(二甲基氨基)萘-1-磺酰胺(丹酰尸胺)
  • DANSYL 尸胺
  • 丹酰尸胺
  • N-丹酰-1,5-戊二胺
  • N-(5-氨基戊基)-5-(二甲基氨基)萘-1-磺酰胺
  • 丹酰戊二胺
  • 10121-91-2
  • Dansylcadaverine, 10 mM in DMSO
  • vacuoles,Inhibitor,probe,Dansylcadaverine,autophagic,Autophagy,autofluorescent,substrate,inhibit
  • N-(5-Aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide[Dansylcadaverine
  • Dansyl cadaverine [5-Dimethylaminonaphthalene-1-(N-(5-aminopentyl))sulfonamide]
  • N-(5-AMINO-PChemicalbookENTYL)-5-DI-METHYL-AMINO-NAPHTHA-LENE-1-SULFON-AMIDE
  • N-(DIMETHYL-AMINO-NAPHTHA-LENE-SULFONYL)-1
  • MONODANSYLCADAVERINE CRYSTALLINE
  • DANSYLCADAVERINE, FOR FLUORESCENCE
  • N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulphonamide
  • DANSYLCADAVERINE MONODANSYLCADAVERINE
  • DANSYLCADAVERINE
  • N-(DIMETHYLAMINONAPHTHALENESULFONYL)-1,5-PENTANEDIAMINE
  • MONODANSYL CADAVERINE
  • N-(5-AMINOPENTYL)-5-DIMETHYLAMINONAPHTHALENE-1-SULFONAMIDE
  • 5-DIMETHYLAMINONAPHTHALENE-1-(N-(5-AMINOPENTYL))-SULFONAMIDE
  • DANSYLCADAVERINE [N-(5-AMINOPENTYL)-5-DIMETHYLAMINONAPHTHALEN-1-SULFONAMIDE];<I>N</I>-<WBR>(5-<WBR>AMINO-PENTYL)<WBR>-<WBR>5-<WBR>DI-METHYL-AMINO-NAPHTHA-LENE-<WBR>1-<WBR>SULFON-AMIDE;<I>N</I>-<WBR>(DIMETHYL-AMINO-NAPHTHA-LENE-SULFONYL)<WBR>-<WBR>1;5-<WBR
  • 5-<WBR
  • <I>N</I>-<WBR>(Dimethyl-amino-naphtha-lene-sulfonyl)<WBR>-<WBR>1
  • <I>N</I>-<WBR>(5-<WBR>Amino-pentyl)<WBR>-<WBR>5-<WBR>di-methyl-amino-naphtha-lene-<WBR>1-<WBR>sulfon-amide
  • Dansylcadaverine [N-(5-AMinopentyl)-5-diMethylaMinonaphthalen-1-sulfonaMide]
  • Einecs 233-326-9
  • N-(5-Aminopentyl)-5-(dimethylamino)-1-naphthalenesulfonamide
  • Monodansyl cadaverine, N-(5-Aminopentyl)-5-dimethylaminonaphthalene-1-sulfonamide, N-(Dimethylaminonaphthalenesulfonyl)-1,5-pentanediamine
  • 1-Naphthalenesulfonamide, N-(5-aminopentyl)-5-(dimethylamino)-

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