APIIN

Chemical Properties

Yellow crystal, soluble in methanol, ethanol, DMSO and other organic solvents, from celery seed, noble spring yellow chrysanthemum Anthemis nobilis, dry parsley Apium graveolens, Matricaria chamomilla [Syn. Matricaria recuJita], small nesting vegetable ircia hirsuta, parsley with crumpled leaves.

Uses

Apiin is an extract flavonoid compound from parsley which shows inhibition towards viral neuramindase. It also shows antiproliferative and apoptotic effects towards human cancer cells.

Definition

ChEBI: A beta-D-glucoside having a beta-D-apiosyl residue at the 2-position and a 5,4'-dihydroxyflavon-7-yl moiety at the anomeric position.

Biological Activity

Apiin, a major flavonoid component of celery, shows antiinflammatory activity mediated through inhibition of nitric oxide synthesis and inhibition of iNOS expression.