ChemicalBook > CAS DataBase List > (+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Structure
(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE
  • CAS No.56715-13-0
  • Chemical Name:(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE
  • CBNumber:CB4230500
  • Molecular Formula:C14H22N2O3
  • Formula Weight:266.34
  • MOL File:56715-13-0.mol
(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Property
  • Melting point 148-152 °C(lit.)
  • Boiling point 508.0±50.0 °C(Predicted)
  • Density 1.125±0.06 g/cm3(Predicted)
  • storage temp. Store at -20°C
  • solubility 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: >6.0 mg/mL
  • pka 13.88±0.20(Predicted)
  • form solid
  • color pale yellow
  • optical activity [α]25/D +16°, c = 1 in 1 M HCl
  • FDA UNII YG132I00WY
  • UNSPSC Code 12352112
  • NACRES NA.22
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: 330884
  • Product name : (R)-(+)-Atenolol
  • Purity: 99%
  • Packaging: 100MG
  • Price: ₹10023.95
  • Updated: 2022/06/14
  • Buy: Buy

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Chemical Properties,Usage,Production

  • Description (+)-Atenolol is an enantiomer of the β1-adrenergic receptor (β1-AR) antagonist (±)-atenolol . (+)-Atenolol inhibits radioligand binding to β-ARs on sarcolemma-enriched membranes (Ki = 8.61 μM). Unlike (–)-atenolol and (±)-antenolol, (+)-atenolol has no effect on blood pressure in spontaneously hypertensive rats.
  • Uses less active enantiomer
  • Uses Antihypertensor
  • Uses Cardioselective β-adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic (class II).
  • Definition ChEBI: The (R)-enantiomer of atenolol.
  • IC 50 β adrenergic receptor
  • References [1] stoschitzky k, egginger g, zernig g, et al. stereoselective features of (r)- and (s)-atenolol: clinical pharmacological, pharmacokinetic, and radioligand binding studies[j]. chirality, 1993, 5(1): 15-19.
(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Preparation Products And Raw materials
Raw materials
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(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Suppliers
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(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Spectrum
56715-13-0, (+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDERelated Search:
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  • 56715-13-0
  • (<i>R</i>)-(+)-Atenolol
  • Prenormin,2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
  • Atenolol Impurity 15 ((R)-Atenolol)
  • (+)-Atenolol
  • (+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE
  • (+)-2-[4-[(2R)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy] phenyl] acetamide
  • (R)-(+)-AtenololHCl
  • (R)-(+)-ATENOLOL
  • (R)-(+)-Atenolol 99%
  • Atenolol R-Isomer
  • (R)-2-(4-(2-hydroxy-3-(isopropylaMino)propoxy)phenyl)acetaMide
  • 4-[(2R)-2-Hydroxy-3-[(1-Methylethyl)aMino]propoxy]benzeneacetaMide
  • Benzeneacetamide, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-, (R)-
  • Benzeneacetamide, 4-[(2R)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-
  • R(+)-ATENOLOL LESS ACTIVE ENANTIOME
  • (R)-(+)-Atenolol,(+)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
  • 2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]ethanamide
  • 2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
  • 2-[4-[(2R)-2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide
  • 4-[(R)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide

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