Follicle-stimulating hormone

Description

Follitropin beta is a human FSH preparation of rDNA origin, which differs chemically from natural FSH and follitropin alfa only by slight variances in the composition of the carbohydrate side chains. In fact, the primary and tertiary structures of both follitropins alfa and beta are indistinguishable from those of human FSH of natural origin. Furthermore, bioassays and physiochemical studies indicate that follitropins alfa and beta are indistinguishable from each other. Therefore, it is not surprising that follitropin beta is approved for the same medical uses as follitropin alpha.