ChemicalBook Product Catalog Organic Chemistry Organic fluorine compound L-ALPHA-LYSOPHOSPHATIDYLCHOLINE

L-ALPHA-LYSOPHOSPHATIDYLCHOLINE

Product NameL-ALPHA-LYSOPHOSPHATIDYLCHOLINE
CAS9008-30-4
CBNumberCB3392256
MFNULL
MW0
EINECS232-715-0
MDL NumberMFCD00131444
MOL FileMol file

Chemical Properties

Density	1.47 g/mL at 20 °C(lit.)
storage temp.	-20°C
solubility	chloroform/methanol (9:1): 50 mg/mL, clear, colorless
form	powder
color	white
biological source	soybean
Cosmetic Ingredient Review (CIR)	L-ALPHA-LYSOPHOSPHATIDYLCHOLINE (9008-30-4)

Safety

PPE	Eyeshields, Gloves, type N95 (US)
Hazard Codes	Xn
Risk Statements	22-38-40-48/20/22-36/38-20/22-63
Safety Statements	36/37-24/25-22-26
RIDADR	UN 1888 6.1/PG 3
WGK Germany	3
RTECS	OG7565000
F	10-21
HS Code	2923200000
Storage Class	11 - Combustible Solids

L-ALPHA-LYSOPHOSPHATIDYLCHOLINE Price

Product number	Packaging	Price	Product description	Buy
Sigma-Aldrich(India) L4129	25MG	₹5270	L-α-Lysophosphatidylcholine from egg yolk ≥99%, Type I, powder	Buy
Sigma-Aldrich(India) L4129	100MG	₹15891.1	L-α-Lysophosphatidylcholine from egg yolk ≥99%, Type I, powder	Buy
Sigma-Aldrich(India) PHR2631	250MG	₹20091.2	Lysophosphatidylcholine Pharmaceutical Secondary Standard; Certified Reference Material	Buy
Sigma-Aldrich(India) L4129	1G	₹56528.15	L-α-Lysophosphatidylcholine from egg yolk ≥99%, Type I, powder	Buy
Sigma-Aldrich(India) L4129	500MG	₹60576.7	L-α-Lysophosphatidylcholine from egg yolk ≥99%, Type I, powder	Buy

L-ALPHA-LYSOPHOSPHATIDYLCHOLINE Chemical Properties,Usage,Production

Uses

L-alpha-Lysophosphatidylcholine (from egg yolk) is a major component of oxidized low density lipoproteins that has been implicated in various inflammatory reactions.

Uses

L-α-Lysophosphatidylcholine from egg yolk has been used:

as a surfactant
as a media supplement and in Staphylococcus aureus inhibition assay in dermatitis
as a demyelinating agent for nerve
as a component in sperm nuclei preparation buffer

Definition

ChEBI: 1-acetyl-sn-glycero-3-phosphocholine is a 1-O-acyl-sn-glycero-3-phosphocholine.

General Description

L-α-Lysophosphatidylcholine is a major plasma lipid, derived from phosphatidylcholines that includes glycerol and sphingoid based lipids with one fatty acid. It is an important cell signaling molecule for G-protein coupled receptors.

Biochem/physiol Actions

L-α-Lysophosphatidylcholine possess cytotoxic effects and is present at high level in ischemia and atherosclerotic aortas.

in vivo

Lysophosphatidylcholines (0.1-20 mg/kg, Oral, single dose) protects against sepsis-induced lethality on albino ICR mice^[4].
Lysophosphatidylcholines (0.1-20 mg/kg, Oral, single dose) enhances bacterial clearance, blocks cecal ligation and puncture (CLP)-induced neutrophil deactivation and increases bactericidal activity of neutrophils^[4].

Animal Model:	Albino ICR mice ^[4]
Dosage:	0.1 mg/kg, 1 mg/kg, 10 mg/kg, 20 mg/kg
Administration:	Oral
Result:	Provided significant protection against cecal ligation and puncture (CLP)-induced lethality at a dose of 1 mg/kg.

IC 50

IL-1β; ERK1; ERK2

L-ALPHA-LYSOPHOSPHATIDYLCHOLINE Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
SUN NUTRAFOODS	+91-11-46710500	ankit.kalra@agrosolvent.com	Beijing，India	10	58
Amitex Agro Products Pvt. Ltd	+91-9892450932	sales@amitexindia.com	Beijing，India	13	58
CLEARSYNTH LABS LTD.	+91-22-45045900	sales@clearsynth.com	Hyderabad，India	6093	58
Otto Chemie Pvt. Ltd.	+91 9820041841	info@ottokemi.com	Mumbai，India	5861	58
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	mktg@pharmaffiliates.com	Haryana，India	6665	58
Nabros Pharma Private Limited	08048372725Ext 851		Ahmedabad，India	2	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 17389186172	1077@dideu.com		3998	58
BINBOBIO CO., LTD.	+8618629063126	info@binbobiological.com		480	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com		21531	55
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com		19934	58

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