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H2N-PEG5-CH2COOH

H2N-PEG5-CH2COOH Structure
H2N-PEG5-CH2COOH
  • CAS No.141282-35-1
  • Chemical Name:H2N-PEG5-CH2COOH
  • CBNumber:CB32656921
  • Molecular Formula:C12H25NO7
  • Formula Weight:295.33
  • MOL File:141282-35-1.mol
H2N-PEG5-CH2COOH Property
  • Boiling point 434.2±40.0 °C(Predicted)
  • Density 1.150±0.06 g/cm3(Predicted)
  • solubility DMSO : 20 mg/mL (67.72 mM; ultrasonic and warming and heat to 60°C)
  • form Solid
  • pka 3.39±0.10(Predicted)
  • color White to off-white
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

H2N-PEG5-CH2COOH Chemical Properties,Usage,Production

  • Uses Amino-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • Biological Activity Amino-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
  • IC 50 PEGs
  • References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
H2N-PEG5-CH2COOH Preparation Products And Raw materials
Raw materials
Preparation Products
H2N-PEG5-CH2COOH Suppliers
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H2N-PEG5-CH2COOH Spectrum
141282-35-1, H2N-PEG5-CH2COOHRelated Search:
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