ChemicalBook > CAS DataBase List > 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone
1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone
1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone
- CAS No.111050-72-7
- Chemical Name:1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone
- CBNumber:CB31394912
- Molecular Formula:C13H16Cl2O4
- Formula Weight:307.17
- MOL File:111050-72-7.mol
1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone Property
- storage temp. 2-8°C
- solubility DMSO: soluble20mg/mL, clear
- form powder
- color white to beige
- UNSPSC Code 12352200
- NACRES NA.77
Safety
- WGK Germany :3
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone Price
More Price(2)
- Brand: Sigma-Aldrich(India)
- Product number: SML0599
- Product name : DIF-1
- Purity: ≥98% (HPLC)
- Packaging: 5MG
- Price: ₹12730.2
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: SML0599
- Product name : DIF-1
- Purity: ≥98% (HPLC)
- Packaging: 25MG
- Price: ₹50249.65
- Updated: 2022/06/14
- Buy: Buy
1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone Chemical Properties,Usage,Production
- Uses DIF-1 is a cell growth suppressor that promotes differentiation in HL-60 cells.
- Definition ChEBI: A differentiation-inducing factor that is hexaphenone bearing two chloro substituents at positions 3 and 5, two hydroxy substituents at positions 2 and 6 as well as a single methoxy substituent at position 4. A secreted, chlorinated molecule that controls ell fate during development of Dictyostelium cells.
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Biological Activity
DIF-1 (differentiation-inducing factor-1) is isolated from a Dictyostelium slime mold, and is used to inhibit proliferation/promote differentiation in various cell lines.', 'DIF-1 is a cell differentiation inducing factor.
Differentiation-inducing factor-1 (DIF-1) blocks the migration and invasion of cells and decreases the expression of matrix metalloproteinase-2. It prevents the proliferation of cells using glycogen synthase kinase-3 (GSK-3)-dependent mechanism. DIF-1 is more active when compared to DIF-2 in promoting stalk cell differentiation under submerged assay conditions.
1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone Preparation Products And Raw materials
Raw materials
Preparation Products
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111050-72-7, 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanoneRelated Search:
- 4-(Hydroxyphenyl)-1-heptanone 3-CHLORO-4-METHOXYBENZALDEHYDE 4-Hexanoylresorcinol 4,6-DICHLORORESORCINOL 4-Hexylresorcinol 3',5'-DICHLORO-2'-HYDROXYACETOPHENONE 3-CHLORO-4-METHOXYACETOPHENONE 2-Chlororesorcinol 1-(3-CHLORO-2-HYDROXYPHENYL)ETHAN-1-ONE 3,5-DICHLOROSALICYLALDEHYDE 1-(3-CHLORO-4-HYDROXYPHENYL)-1-ETHANONE 2-CHLORO-3-METHOXYPHENOL 1-(3,5-DICHLORO-2-HYDROXYPHENYL)PROPAN-1-ONE 3',5'-DICHLORO-4'-HYDROXYACETOPHENONE 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone SALOR-INT L498912-1EA 3,5-DICHLORO-4-HYDROXYBENZALDEHYDE DIF-3
- C13H16Cl2O4
- DIF-1,CELL PROLIFERATION抑制剂
- 111050-72-7
- DIF-1, cell proliferation inhibitor
- 1-Hexanone, 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)-
- 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexane-1-one
- 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one
- 1-(3,5-Chloro-2,6-dihydroxy-4-methoxyphenyl)-1-Hexanone
- 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone